Modern methodology for improving bone tissue regeneration in dentistry

Authors

DOI:

https://doi.org/10.26641/1997-9665.2025.3.8-14

Keywords:

bone tissue, osteoregeneration, remodeling

Abstract

The aim of this study is to investigate modern techniques for improving bone tissue regeneration. To achieve this goal, we reviewed sources from domestic and international scientific medical literature. Results. Maxillary bone loss can result from chronic dental diseases, trauma, or tumor resection. Bone resorption, most often caused by infection or inflammation, can lead to discomfort, deformity, and complications during dental implant placement. While implants can restore oral function, many patients lack sufficient bone volume for their placement. Therefore, several techniques are used to address this problem. Guided bone regeneration promotes the growth of new bone in damaged areas of the jaw. Despite its effectiveness, this method can be time-consuming to achieve sufficient bone volume. The PASS principle (Primary closure, Angiogenesis, Space maintenance, and Stability) is considered fundamental for successful guided bone regeneration. Guided tissue regeneration utilizes two main types of barrier membranes: resorbable and non-resorbable membranes. Recent advancements in titanium mesh technology include individually pre-bent meshes tailored to specific defect geometries. Distraction osteogenesis offers significant advantages over traditional bone grafting techniques, eliminating the need for donor bone and avoiding complications associated with donor site morbidity. Despite its advantages, distraction osteogenesis is associated with certain challenges. Platelet-rich plasma (PRP) is gaining popularity in dentistry due to its ability to accelerate healing and promote tissue regeneration. PRP's capacity to release high concentrations of growth factors makes it an effective tool in stimulating stem cell activity, promoting tissue healing, and enhancing bone and soft tissue regeneration. Stem cell therapy holds significant promise for the regeneration of teeth, bone tissue, and periodontal structures, making it a key area in modern dental tissue engineering. Conclusion. A review of the scientific literature reveals some inconsistencies regarding the effectiveness of the aforementioned guided bone regeneration techniques and an understanding of the situational variations in bone tissue reconstruction across different clinical scenarios. Modern techniques for improving bone tissue regeneration aim to create optimal conditions for natural bone regeneration through the use of biocompatible materials, guided surgical techniques, biologically active factors, and individualized approaches based on a deep understanding of bone tissue histoarchitecture. A significant number of scientific works, both experimental and clinical, are dedicated to the study of osteoregeneration; however, under current conditions, a correct understanding of the sequence and timeframes of osteogenic regenerative processes is of particular importance. Therefore, the pursuit of further research into modern techniques and their associated dynamics of histoarchitectural remodeling during bone defect healing is justified. This will allow for the development of personalized osteoregeneration strategies tailored to the needs of the individual patient.

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Published

2025-10-30

How to Cite

Dzupa , P., Stoj , O., & Chelpanova , I. (2025). Modern methodology for improving bone tissue regeneration in dentistry. Morphologia, 19(3), 8–14. https://doi.org/10.26641/1997-9665.2025.3.8-14

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Vol. 19 No. 3 (2025)

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