Dušan Lambl: the fate of scientific discoveries and the professional ethics of the great pathologist

Authors

DOI:

https://doi.org/10.26641/1997-9665.2020.3.192-200

Keywords:

Dušan Lambl, biography, autopsy, Chilomastix davainei, Entamoeba histolytica, Acanthocephala, Giardia lamblia, Lambl's excrescences

Abstract

Background. The great pathologist Dušan Lambl (1824–1895; Czech by origin, who lived half of his life in the Russian Empire, of which 10 years – in Kharkiv) made an invaluable contribution to the development of medical science. However, his discoveries were gradually forgotten and faded from the names of the pathogens discovered by him and the diseases they cause. Objective. Studying Lambl's scientific heritage and information about his professional activities can help restore knowledge about his scientific contribution and learn valuable lessons that could help modern specialists in their professional identification and incorporation. Methods. Analysis of literature about Lambl, his discoveries and professional activities using general scientific and historical methods allowed us to come to certain conclusions. Results. In the late 1850s, persecuted by the authorities as a member of the national movement, Lambl was forced to seek refuge in Ukraine, where in 1861 he took up the vacant position of professor at the Department of Anatomy of the Medical Faculty of Kharkiv University. By that time, a world-renowned pathologist, Lambl started to actively develop the teaching of Pathological anatomy and Histology at the University. In 1867, through his efforts, two new departments were established at the faculty – Histology and Pathological anatomy. The latter he headed personally until his departure to Warsaw in 1871. The surviving materials on Lambl's activities in Kharkiv are showing him as a skilful pathologist with a refined approach to his profession. Analysis of the literature on Lambl's scientific researches demonstrated a slow fading of references to his name in the titles of his discoveries. Conclusion. Lambl's contribution to scientific medicine is indeed great, but not appreciated deservedly. His approach to the professional activity of a pathologist and teacher can become a great example for young specialists in practical medicine, science and education.

References

  1. Státní oblastní archiv v Plzni. F. 1014. Sbírka matrik západních Čech. Letiny 01. 1784-1883 r. 243 l.
  2. Labusova D. Vilém Dušan Lambl (1824-1895), Jan Křtitel Lambl (1826-1909), Anna Cardová-Lamblová (1836-1919). Soupis osobniho fondu. Praha, 1996. 21 s.
  3. Lipoldová M. Giardia and Vilém Dušan Lambl. Singer SM. PLoS Negl Trop Dis. 8(5):e2686.
  4. Popov MA. Professor Dushan Fedorovych Liambl, eho sluzhebnaia y lyteraturnaia deiatelnost [Professor Dusan Fedorovich Lambl, his service and research activities]. Kharkiv: Adolf Darre; 1896. 277 p.
  5. Ševčenková P. Edice soupisů tzv. politicky kompromitovaných pro Prahu z roku 1857: neoabsolutistická perzekuce v Čechách ve světle úřední evidence. Paginae historiae: sborník Národního archive. Praha: Národní archiv 14; 2006:355-481.
  6. Kilian J. 110 výrocí úmrtí lékare a vlastence Viléma Dusana Lambla (1824-1895) [110th anniversary of the death of the physician and patriot Vilém Dusan Lambl (1824-1895)]. Cas Lek Cesk. 2005;144(12):847-848. Czech.
  7. Popov MA. Prozektor Yppolyt Osypovych Vylkomyrskyi. Zapysky Ymperatorskoho Kharkovskoho unyversyteta. Letopys Kharkovskoho unyversyteta. [Mitrofan Popov. Prosector Ippolit Osipovich Vilkomirsky] Kharkiv: University publishing; 1895. 3:1-83.
  8. Lambl DF. Patolohycheskaia anatomyia. V.1. Osteopathologia: zapysky studenta Ya. Kremianskoho po chtenyiam Liamblia v Kharkovskom unyversytete v 1861-62 akad. hodu. [Pathological anatomy. Vol. 1. Osteopathology: notes by student Y. Kremyansky on Lamb readings at Kharkov University in the academic year 1861–62.]. Kharkiv: Lytohrafyia Y. Popova; 1861. 136 с.
  9. Lambl DF. Patolohycheskaia anatomyia. V.2. Osteopathologia et Arthropathologia: zapysky studenta Ya. Kremianskoho po chtenyiam Liamblia v Kharkovskom unyversytete v 1861-62 akad. hodu. [Pathological anatomy. Vol. 2. Osteopathology with Arthpathology: notes by student Y. Kremyansky on Lamb readings at Kharkov University in the academic year 1861–62.]. Kharkiv: Lytohrafyia Y. Popova; 1862. 81-168 p.
  10. Lambl DF. Patolohycheskaia anatomyia. V.3. Pseudoplasmata: zapysky studenta Ya. Kremianskoho po chtenyiam Liamblia v Kharkovskom unyversytete v 1861-62 akad. hodu. [Pathological anatomy. Vol. 3. Anatomy of growths or tumors: notes by student Y. Kremyansky on Lamb readings at Kharkov University in the academic year 1861–62.]. Kharkiv: Lytohrafyia Y. Popova; 1862. 88 p.
  11. Lambl DF. Patolohycheskaia anatomyia. V.4. Dermato-pathologia: zapysky studenta N. Afanaseva po chtenyiam Liamblia v Kharkovskom unyversytete v 1864–65 akad. hodu. [Pathological anatomy. Vol. 4. Dermato-pathology: notes by student N. Afanasiev on Lamb readings at Kharkov University in the academic year 1864–65.]. Kharkiv: Lytohrafyia Butenkovoi; 1865. 114 p.
  12. Medytsynskyi fakultet Kharkovskoho unyversyteta za pervye 100 let ego sushchestvovanyia (1805-1905) [The Medical school of Kharkov University for the first 100 years of its existence (1805-1905)]. Kharkiv: University publishing; 1905-1906. 471, 314, ХV p.
  13. Meyer, G. Ueber die Structurverhältnisse des Annulus ciliaris bei Menschen und Säugethieren. Archiv f. pathol. Anat. 34, 380–400 (1865). https://doi.org/10.1007/BF02323019.
  14. Lambl V. Papilläre Excrescenzen an der Semilunar-Klappe der Aorta. Wien Med Wochenschr. 1856. 16:244-247.
  15. Aziz F, Baciewicz FA. Lambl's excrescences: review and recommendations. Tex Heart Inst J. 2007; 34 (3):366-368.
  16. Kamran H, Patel N, Singh G, Pasricha V, Salifu M, McFarlane SI. Lambl's excrescences: A case report and review of the literature. Clin Case Rep Rev. 2016;2(7):486-488. doi:10.15761/CCRR.1000254
  17. Salehi Omran S, Chaker S, Lerario MP, Merkler AE, Navi BB, Kamel H. Relationship between Lambl's excrescences and embolic strokes of undetermined source. Eur Stroke J. 2020;5(2):169-173. doi:10.1177/2396987319901201.
  18. Elkattawy S, Noori MAM, Sah A, Hasan Kazmi SM, Desai D. Lambl's Excrescences Associated With Left Frontal Ischemic Stroke: A Case Report. Cureus. 2020;12(7):e9371. Published 2020 Jul 24. doi:10.7759/cureus.9371
  19. Hirayama T, Morioka H, Fujiwara H, et al. An Autopsy Case of Lambl's Excrescences with Trousseau Syndrome that Caused Cardioembolic Stroke [published online ahead of print, 2020 Aug 4]. Intern Med. 2020;10.2169/internalmedicine.5162-20. doi:10.2169/internalmedicine.5162-20
  20. Leuckart R. The parasites of man, and the diseases which proceed from them: a text-book for students and practitioners [Translated from the German, with the co-operation of the author by W. E. Hoyle]. Edinburgh: Young J. Pentland; 1886. 771 p.
  21. Leuckart R. Die parasiten des menschen und die von ihnen herruhrenden krankheiten. Leipzig-Heidelberg: C.F.Wintersche Verlagshandlung; 1879-1886. 1000 s.
  22. Lambl V. Mikroskopische Untersuchungen der Darm-Excrete. Beitrag zur Pathologie des Darms zur Diagnostik am Krankenbette. Vierteljahrschrift für die praktische Heilkunde. Herausgegeben von der medicinischen Facultät in Prag. 1859. 61:1-58.
  23. Lambl V. Über Harnbalsenkrebs. Ein Beitrag zur mikroskopischen Diagnostik am Krankenbette. Vierteljahrschrift für die praktische Heilkunde. Herausgegeben von der medicinischen Facultät in Prag. Prag.: Verlag von Karl Andre. 1865. S. 1-32
  24. Ford BJ. The discovery of Giardia. The Microscope. 2005. 53(4):147-153.
  25. Schmidt GD. Acanthocephalan Infections of Man, with Two New Records. The Journal of Parasitology. 1971;57(3):582. doi: 10.2307/3277920
  26. Lambl W. Beobachtungen und Studien aus dem Gebiete der pathologischen Anatomie und Histologie. Prag: Verlag von Friedrich Tempsky, 1860. 384 s.
  27. Chidester FE. Zoology. A textbook for College and university students. New York: D. van Nostrand company, inc., 1932. 581 p.
  28. Lösch, F. Massenhafte Entwickelung von Amöben im Dickdarm. Archiv f. pathol. Anat. 65, 196–211 (1875). https://doi.org/10.1007/BF02028799.
  29. Behla R. Die amöben insbesondere vom parasitären und culturellen Standpunkt. Berlin: Verlag vo'n August Hirschwald, 1895. 73 s.
  30. Calkins GN. The protozoa. New York-London: The Macmillan company. 1901. 347 p.
  31. Lesh FA. Massive development of amebas in the large intestine. Fedor Aleksandrovich Lesh (Lösch). Am J Trop Med Hyg. 1975;24(3):383-392. doi:10.4269/ajtmh.1975.24.383.
  32. Osler W. The Principles and Practice of Medicine Designed for the Use of Practitioners and Students of Medicine. JAMA. 1936; 106(7):566. doi:10.1001/jama.1936.02770070062035.
  33. Arellano-Aguilar G, Marín-Santillán E, Castilla-Barajas JA, Bribiesca-Juárez MC, Domínguez-Carrillo LG. A brief history of amoebic liver abscess with an illustrative case. Breve historia del absceso hepático amebiano, con un caso ilustrativo. Rev Gastroenterol Mex. 2017; 82(4):344-348. doi:10.1016/j.rgmx.2016.05.007
  34. Hegner RW. Giardia and Chilomastix from Monkeys, Giardia from the Wild Cat and Balantidium from the Sheep // The Journal of Parasitology, Dec., 1924, Vol. 11, No. 2, pp. 75-78. doi:10.2307/3270864
  35. Leiva L. Observations on Chilomastix intestinalis Kuczinski. The Journal of Parasitology. 1921. 8(2):49-57. doi:10.2307/3270749
  36. Alexeieff A. Sur quelques noms de genres de Flagellés qui doivent disparaître de la nomenclature pour cause de synonymie ou pour toute autre raison. Diagnoses de quelques genres récemment étudiés. Zoologischer Anzeiger. 1912. 39: 674–680.
  37. Kofoid CA. A critical review of the nomenclature of human intestinal flagellates, Cercomonas, Chilomastix, Trichomonas, Tetratrichomonas, and Giardia. University of California publications in zoology. 1920. 20:145-168.

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Protsenko, O. S., Kyrychenko, M. I., & Remnyova, N. O. (2020). Dušan Lambl: the fate of scientific discoveries and the professional ethics of the great pathologist. Морфологія / Morphologia / Morfologìâ, 14(3), 192–200. https://doi.org/10.26641/1997-9665.2020.3.192-200

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Vol. 14 No. 3 (2020)

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