Morphological diagnostics of pathology of the thorax organs in HIV-infected patients of a phthisiopulmonology hospital.

Authors

DOI:

https://doi.org/10.26641/1997-9665.2019.4.24-33

Keywords:

HIV infection, pathology of the thorax, morphological diagnostics, minimally invasive procedures

Abstract

Background. Intravital differential diagnostics of HIV-associated of the thorax pathology is complex. Currently in the diagnostic algorithm various mini-invasive diagnostic procedures with morphological examination of biopsy material are widely used. Objective – to evaluate the effectiveness of the morphological diagnostics of the thorax diseases in HIV-infected patients. Methods. A retrospective analysis of 205 cases of a morphological study of a biopsy and surgical material from hospitalized HIV-infected patients of a phthisiopulmonological profile over a 5-year period was carried out. Comparison of the histological conclusion with the final clinical diagnosis was made. Results. Among all hospitalized HIV patients in 45,5 % of cases in the diagnostic algorithm of the thorax pathology there was a need for a morphological study. Endoscopic procedures with a biopsy were performed in 93,6 % of cases; typical surgeries – in 5,8 % of cases. In 60,0 % of cases the material was obtained in video assisted thoracoscopy. Histological examination of the lungs was carried out in 23,4 %, lymph nodes in 25,4 % and parietal pleura in 50,7 % of cases. Conclusion. In 77,1 % of cases of all histological studies the final clinical diagnosis and histological conclusion coincided. In 12,7 % of the histological examination there was a clarification of the preliminary clinical diagnosis. The effectiveness of histological diagnostics of thorax diseases in HIV-infected patients was: lung pathology – 81,3 %, lymphatic system pathology – 84,6 % and pleural pathology – 95,2 %. The overall effectiveness of histological examination of biopsy and surgical material among hospitalized HIV-infected patients was 89,8 %.

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Liskina, I. V., Silchenko, V. P., Zahaba, L. M., & Kuzovkova, S. D. (2019). Morphological diagnostics of pathology of the thorax organs in HIV-infected patients of a phthisiopulmonology hospital. Морфологія / Morphologia / Morfologìâ, 13(4), 24–33. https://doi.org/10.26641/1997-9665.2019.4.24-33

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Vol. 13 No. 4 (2019)

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