Differential diagnosis of pathomorphological changes in the lungs of pregnant children in certain components of the metabolic syndrome of the mother.
DOI:
https://doi.org/10.26641/1997-9665.2019.3.115-119Keywords:
differential diagnosis, metabolic syndrome, preterm infantsAbstract
Backgroud. The metabolic syndrome of the mother and the effect of its components on the fetal development is the focus of medical science and health care. Also known that it is the close relationship between functional immaturity of the organs and tissues of the fetus and comorbidities of the mother, especially type 2 diabetes, hypertension, obesity and dyslipidemia. Objective is to carry out differential diagnosis of pathomorphological changes in the lungs of premature infants in the study groups. Methods. The studies were performed on the section material of the lungs of premature infants of 29-33 weeks of gestation (120 cases), which were divided into three groups depending on the components of the metabolic syndrome of the mother. Results. Moderate swelling of the mucous membrane, areas of blood filling, venous plethora, mucous membrane in segmental bronchial tubes of children of group I are observed. Segmental bronchi of children of group II corrugated and swollen, hyperplastic growths of the ciliated prismatic epithelium are observed. In group III of the study, the mucous membrane of the segmental bronchi is represented by a multilayered ciliated cylindrical epithelium; Morphometric parameters of the epithelial cells of the respiratory parts of the lungs of premature infants in the three study groups indicate a lag in their differentiation processes, which delay the structural and functional development of lung tissue. Conclusion. Differential diagnostics of pathomorphological changes in the lungs of premature infants in the study groups revealed immaturity of the lung tissue, which corresponds to the specified gestation periods, and their morphological changes are related to the influence of maternal factors, such as hypertension, diabetes mellitus, diabetes mellitus.
References
- Avramenko TV. [Osoblyvosti hormonalno-metabolichnykh protsesiv v orhanizmi vahitnykh z tsukrovym diabetom ta yikh vplyv na stan ploda i novonarodzhenoho]. Visnyk naukovykh doslidzhen. 2004;2:114-116. Ukrainian.
- Berykhanova RR, Khrypunova HY. [Osobennosty techenyia beremennosty y rodov u patsyentok s ozhyrenyem]. Akusherstvo y hynekolohyia. 2007;5: 9-12. Ukrainian.
- Dedov II, Shestakova MV. [Saharnyiy dIabet i arterialnaya gipertenziya]. M.: SchSchSch «Meditsinskoe informatsionnoe agentstvo». 2006; 344p. Russian.
- Doschitsin VL, Drapkina OM. [Arterialnaya gipertenziya pri metabolicheskom sindrome]. Rossiyskiy kardiologicheskiy zhurnal. 2006;5(61):64-67. Russian.
- Lebedeva OV. [Osobennosti sostoyaniya gemodinamiki u novorozhdennyih s respiratornyim distress-sindromom]. Materialyi mezhregionalnoy nauchno-prakticheskoy konferentsii «Aktualnyie problemyi kardiologii detey i vzroslyih. 2007;Astrahan:90–94. Russian.
- Menshykova AO, Dobrianskyi DO. [Osoblyvosti perebihu respiratornoho dystres-syndromu u nedonoshenykh novonarodzhenykh zalezhno vid vydu dykhalnoi pidtrymky]. Neonatolohiia, khirurhiia ta perynatalna medytsyna. 2016;VI(3):13-18.
- Nagaeva EV. [Vnutriutrobnaya zaderzhka rosta]. Pediatriya. 2009;88(5):140 146. Russian.
- Shunko YeIe, Konchakovska TV. [Respiratornyi dystres-syndrom novonarodzhenykh: problemy ta perspektyvy profilaktyky i likuvannia z pozytsii dokazovoi medytsyny]. Mystetstvo likuvannia. 2005;2:50-53. Ukrainian.
Downloads
How to Cite
Issue
Section
License
Copyright (c) 2019 Morphologia
This work is licensed under a Creative Commons Attribution 4.0 International License.
The authors reserve the right to authorship of their work and transfer to the Journal the right to the first publication of this work under the terms of a license Creative commons Attribution 4.0 International (CC BY 4.0), which allows other people to freely distribute the published work with a mandatory reference to the authors of the original work and the first publication of the work in this journal.By submitting a manuscript to the editorial office of the Journal ‘Morphologia’ authors agree to transfer the rights to protect and use the manuscript (all supplemental materials, particularly protected objects such as photos, drawings, diagrams, tables, etc.), including the reproduction in the press and distribution via the Internet; translation of the manuscript into any language; export and import of journal copies with the Authors’ article in order to make it available for public. Authors convey the rights mentioned above to the editorial office without any temporal or territorial limitation all over the world.
The Authors guarantee that they have the exclusive rights to use the material transferred to editorial office. Editors are not responsible to third parties for contraventions of warranty given by the Authors. The considered rights are transferred to the editorial office since the moment when the current issue is signed for publishing. Reproduction of materials published in the Journal by other individuals and legal entities is possible only with the consent of Editorial office, with the obligatory indication of the full bibliographic reference of the primary publication. The Authors reserve the right to use the published material, its fragments and parts for teaching materials, oral presentations, dissertation thesis prepararion with obligatory bibliographic citation of the original paper. Electron copy of the published article, downloaded from official journal web-site in .pdf format may be put by authors on the official web-site of their institutions, any other official resources with open access.
