Pathomorphologocal aspects of the recurrence development of the lower extremities varicose veins.

Authors

  • O. G. Kuryk State Scientific Institution "Scientific-Practical Centre of Preventive and Clinical Medicine", State Administration of Affairs, Kyiv, Ukraine, Ukraine https://orcid.org/0000-0003-3093-4325
  • Yu. M. Hupalo State Scientific Institution "Scientific-Practical Centre of Preventive and Clinical Medicine", State Administration of Affairs, Kyiv, Ukraine, Ukraine https://orcid.org/0000-0002-9467-115X
  • О. І. Nabolotnyi State Scientific Institution "Scientific-Practical Centre of Preventive and Clinical Medicine", State Administration of Affairs, Kyiv, Ukraine, Ukraine https://orcid.org/0000-0002-4273-5799
  • O. E. Shved State Scientific Institution "Scientific-Practical Centre of Preventive and Clinical Medicine", State Administration of Affairs, Kyiv, Ukraine, Ukraine https://orcid.org/0000-0002-7652-9301
  • V. V. Shaprinskiy State Scientific Institution "Scientific-Practical Centre of Preventive and Clinical Medicine", State Administration of Affairs, Kyiv, Ukraine, https://orcid.org/0000-0002-1437-7410
  • D. Yu. Shapovalov State Scientific Institution "Scientific-Practical Centre of Preventive and Clinical Medicine", State Administration of Affairs, Kyiv, Ukraine, Ukraine https://orcid.org/0000-0001-7419-9559
  • A. V. Shamray-Sas State Scientific Institution "Scientific-Practical Centre of Preventive and Clinical Medicine", State Administration of Affairs, Kyiv, Ukraine, Ukraine https://orcid.org/0000-0003-4099-3118

DOI:

https://doi.org/10.26641/1997-9665.2019.1.13-20

Keywords:

lower extremities varicose veins, recurrence development, neovascularization, morphological features

Abstract

Backgroud. Recurrence development of varicouse disease of lower extremities continues to be a topical issue and requires further study from both the surgeons and the morphologists. Neovascularization is considered one of the main causes of the recurrence develoment of varicose veins of the lower extremities. Objective. The aim is to study the morphological features of recurrent veins in the stump region of the great saphenous vein. Methods. A morphological study of varicose veins was performed in 12 patients after the surgical treatment of non- saphenous recurrent varicose veins of the lower extremities. Results. The hypertrophy and sclerosis of the walls with a predominance of changes in the muscle layer of the vascular wall was found. The subendothelial layer was unevenly thickened due to the hypotrophy of smooth muscle fibers and the development of sclerotic changes with diffuse proliferation of collagen and elastic fibers. The outer shell was thickened due to the hypertrophy of the longitudinal bundles of smooth myositis and the thickening of the connective tissue part of the shell. It was noted uneven thickening of the veins’ walls. We observed both veins with a typical three-layer wall, and "defective" vessels with a thin wall. In the veins with a three-layer wall, local thickening and thinning of the wall were observed, and the wall was crimped. In some vessels there was no middle shell. In part of the veins, detachment of the endothelium was noted with the formation of structures by the type of thin-walled vessels inside the lumen of the veins. There were also single "defective" vessels formed with a thin wall, an elongated lumen, which were among the connective and adipose tissue. In one case, the vessels in the lymph node were found - elongated, with a thin wall, with a slit lumen, and also dilated, sometimes with a thin wall, with an irregularly shaped lumen. Conclusion. Neovascularization is the process of the formation of vessels of different caliber, with a different histological structure - from defective vessels with a thin wall to vessels with a three-layer wall structure. It is important to observe the formation of blood vessels in the lymph nodes.

References

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How to Cite

Kuryk, O. G., Hupalo, Y. M., Nabolotnyi О. І., Shved, O. E., Shaprinskiy, V. V., Shapovalov, D. Y., & Shamray-Sas, A. V. (2019). Pathomorphologocal aspects of the recurrence development of the lower extremities varicose veins. Морфологія / Morphologia / Morfologìâ, 13(1), 13–20. https://doi.org/10.26641/1997-9665.2019.1.13-20

Issue

Vol. 13 No. 1 (2019)

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Статті

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Copyright (c) 2019 Kuryk O.G., Hupalo Yu.M., Nabolotnyi О.І., Shved O.E., Shaprinskiy V.V., Shapovalov D.Yu., Shamray-Sas A.V., Morphologia

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