The angiogenesis.

Authors

  • M. V. Sprindzuk United Institute Informatics Problems of the National Academy of Sciences of Belarus, Belarus

DOI:

https://doi.org/10.26641/1997-9665.2010.3.4-13

Keywords:

angiogenesis, neovascularization, vascular endothelial growth factor, metastasis, cancer, malignant tumors, antiangiogenic pharmacotherapy

Abstract

The research theme of angiogenesis: the development of blood vessels from preexisting ones is one of the most financially supported medical scientific topics in the world. It is connected with the fact, that 500 000 000 people require the therapeutic correction of the pathological processes of angiogenesis. In the review article only the brightest research articles knowingly predominantly Russian are systematized. The paper is well illustrated, to provide the understandable educational resource. The biochemical and pathophysiological questions of angiogenesis are discussed in close relation to the modern angiogenic pharmacotherapy. The purpose of the article is to present to the reader an opportunity to discover the biomedical research challenge of the 21 century: the pathological blood supply, vascularization and the associated phenomena.

References

  1. Коган Е. А. Автономный рост и прогрессия опухолей / Коган Е. А. // Российский журнал гастроэнтерологии, гепатологии, колопроктологии. – 2002. – Т. 12, № 4. – С. 45-49.
  2. Махачев С. М. Механическое стимулирование ангиогенеза / С. М. Махачев, А. О. Османов, М. Р. Рамазанов. – М. : Медицина, 2003. – 160 с.
  3. Прозоровский В. Кровеносные сосуды и рак / В. Прозоровский // Наука и жизнь. – 2006. – № 9. – С. 9-14.
  4. Роль ангиогенеза в развитии наружного генитального эндометриоза / Д. И. Соколов, П. Г. Кондратьева, В. Л. Розломий [и др.] // Цитокины и воспаление. – 2007. – Т. 6, № 2. – С. 10-17.
  5. Фактор роста эндотелия сосудов как показатель гипоксии тканей, его возможная роль в патогенезе плоского лишая слизистой оболочки рта / Л. В. Петрова, Н. Е. Кушлинский, Л. В. Ильина // Вестник дерматологии и венерологии. – 2004. – № 5. – С. 7-8.
  6. Angiogenesis inhibition with bevacizumab and the surgical management of colorectal cancer / A. D. Thornton, P. Ravn, M. Winslet, K. Chester // British Journal of Surgery Society Ltd. – 2006. – Vol. 93, № 12. – P. 1456-6.
  7. Carmeliet P. Angiogenesis in cancer and other desease / P. Carmeliet, R. Jain // Nature. – 2000. – Vol. 407. – P. 249-257.
  8. Carmeliet P. Angiogenesis in health and disease / Carmeliet P. // Nature medicine. – 2003. – Vol. 9. – P. 653-660.
  9. Carmeliet P. Angiogenesis in life, disease and medicine / Carmeliet P. // Nature. – 2005. – Vol. 438. – P. 932-936.
  10. Carmeliet P. Mechanisms of angiogenesis and arteriogenesis / Carmeliet P. // Nature medicine. – 2000. – Vol. 6, № 4. – P. 389-395.
  11. Cooke R. Dr. Folkman's war angiogenesis and the struggle to defeat cancer / R. Cooke // New York : Random House, 2001. - 366 p.
  12. Folkman J. A new link in ovarian cancer angiogenesis: lysophosphatidic acid and vascular endothelial growth factor expression / Folkman J. // J. Natl. Cancer Inst. – 2001. – Vol. 93, № 10. – P. 734-735.
  13. Folkman J. Clinical applications of research on angiogenesis / Folkman J. // New England Journal of Medicine. – 1995. – Vol. 333, № 26. – P. 1757-1763.
  14. Folkman J. What is the evidence that tumors are angiogenesis dependent? / J. Folkman // J. Natl. Cancer Inst. – 1990. – Vol. 82, № 1. – Р. 4-6.
  15. Forough R. New Frontiers in Angiogenesis / R. Forough. – Netherlands : Springer, 2006. – 203 p.
  16. Kerbel R. S. Tumor Angiogenesis / Robert S. Kerbel // N. Engl. J. Med. – 2008. – Vol. 358. – P. 2039-2049.
  17. Ribatti D. History of research on tumor angiogenesis / D. Ribatti // Netherlands : Springer, 2009. – 125 p.

Downloads

How to Cite

Sprindzuk, M. V. (2010). The angiogenesis. Морфологія / Morphologia / Morfologìâ, 4(3), 4–13. https://doi.org/10.26641/1997-9665.2010.3.4-13

Issue

Vol. 4 No. 3 (2010)

Section

Статті

License

Copyright (c) 2010 Sprindzuk M.V., Morphologia

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

 The authors reserve the right to authorship of their work and transfer to the Journal the right to the first publication of this work under the terms of a license Creative commons Attribution 4.0 International (CC BY 4.0), which allows other people to freely distribute the published work with a mandatory reference to the authors of the original work and the first publication of the work in this journal.
        By submitting a manuscript to the editorial office of the Journal ‘Morphologia’ authors agree to transfer the rights to protect and use the manuscript (all supplemental materials, particularly protected objects such as photos, drawings, diagrams, tables, etc.), including the reproduction in the press and distribution via the Internet; translation of the manuscript into any language; export and import of journal copies with the Authors’ article in order to make it available for public. Authors convey the rights mentioned above to the editorial office without any temporal or territorial limitation all over the world. 
        The Authors guarantee that they have the exclusive rights to use the material transferred to editorial office. Editors are not responsible to third parties for contraventions of warranty given by the Authors. The considered rights are transferred to the editorial office since the moment when the current issue is signed for publishing. Reproduction of materials published in the Journal by other individuals and legal entities is possible only with the consent of Editorial office, with the obligatory indication of the full bibliographic reference of the primary publication. The Authors reserve the right to use the published material, its fragments and parts for teaching materials, oral presentations, dissertation thesis prepararion with obligatory bibliographic citation of the original paper. Electron copy of the published article, downloaded from official journal web-site in .pdf format may be put by authors on the official web-site of their institutions, any other official resources with open access.