Migration paths of cells different origins in the embryonic human heart.
DOI:
https://doi.org/10.26641/1997-9665.2010.3.14-17Keywords:
myocardium, neurofilaments, blood cells, migration, embryonic human heartAbstract
Hearts of human embryos were investigated using immunohistochemical method with antibodies to neurofilaments from 4 to 8 week of prenatal development. It was found that the embryonic human heart there are NF-positive cells, which occupy its territory by two mechanisms: through the migration of intercellular spaces and on the mechanism immersion out of heart cavity. In the second case neurofilaments-positive cells through the endothelium of blood vessels or endocardium immersion into the myocardium or mesenchymal areas. Mesenchyme in the heart contain neurofilament-positive cells, migrating here from both mechanisms. Similar cells have been found by us in the liver of human embryo, beginning at 5 weeks of prenatal development.
References
- Вермель А. Е. Стволовые клетки: общая характеристика и перспективы применения в клинической практике / А. Е. Вермель // Клин. медиц. - 2004. - № 1. - С. 5-11.
- Влияние интрамиокардиальной трансплантации мононуклеарных клеток костного мозга на электро-механическое сопряжение кардиомиоцитов крыс после криодеструкции миокарда / С. А. Афанасьев, И. Н. Свиридов, В. П. Шахов [и др.] / Вест. аритмологии. - 2007. - № 47. - С. 38-41.
- Дотримання етичних та законодавчих вимог при виконанні наукових морфологічних досліджень (методичні рекомендації) / [В. Л. Кулініченко, В. Д. Мішалов, Ю. Б. Чайковський та ін.]. - Київ, 2007. - 29 с.
- Сілкіна Ю. В. Імуногістохімічна ідентифікація провідних кардіоміоцитів в ембріональному серці / Ю. В. Сілкіна, І. В. Твердохліб // Вісник морфології. - 2009. - № 1. - С. 51-54.
- Острый коронарный синдром и клеточные технологии / Ю. И. Бузиашвили, С. Т. Мацкеплишвили, Б. Г. Алекян [и др.] // Вест. Российской АМН. - 2005. - № 4. - С. 65-69.
- Adult reserve stem cells and their potential for tissue engineering / H. Young, C. Duplaa, M. Romero-Ramos [et al.] // Cell Biochem. Biophys. - 2004. - Vol. 40, № 1. - P. 1-80.
- Davenport R. Lucky or Good? Stem cells' all-around talent disputed (Stem cells) / R. Davenport // Sci. Aging Knowl. Environ. - 2002. - Vol. 120, № 11. - Р. 36-45.
- Differentiation of bone marrow-derived stem cells in injured rat brain tissue / X. Zou, H. Zhang, C. Zhao [et al.] // Di Yi Jun Yi Da Xue Xue Bao. - 2004. - Vol. 24, № 10. - Р. 1102-1106.
- Leo A. Mesenchymal stem cells in tissue engineering / A. Leo, D. Grande // Cells Tissues Organs. - 2006. - Vol. 183, № 3. - Р. 345-352.
- Mezey E. Bone marrow: a possible alternative source of cells in the adult nervous system / E. Mezey, K. Chandross // Europ. J. of Pharmac. - 2000. - Vol. 405, № 1-3. - Р. 297-302.
- Orlic D. Stem cells for myocardial regeneration / D. Orlic, J. Hill, A. Arai // Circ. Res. - 2002. - Vol. 91. - P. 1092-1099.
- Priller J. Grenzgänger: adult bone marrow cells populate the brain / J. Priller // Histochemistry and Cell Biology. - 2003. - Vol. 120, № 2. - Р. 85-91.
- Stem cell therapy in amyotrophic lateral sclerosis: a methodological approach in humans / L. Mazzini, F. Fagioli, R. Boccaletti [et al.] // Amyotrophic Lateral Sclerosis. - 2003. - Vol. 4, №. 3. - P. 158-161
Downloads
How to Cite
Voloshin, N. A., & Chaykovsky, Y. B. (2010). Migration paths of cells different origins in the embryonic human heart. Морфологія / Morphologia / Morfologìâ, 4(3), 14–17. https://doi.org/10.26641/1997-9665.2010.3.14-17
Issue
Section
Статті
License
Copyright (c) 2010 Morphologia

This work is licensed under a Creative Commons Attribution 4.0 International License.
The authors reserve the right to authorship of their work and transfer to the Journal the right to the first publication of this work under the terms of a license Creative commons Attribution 4.0 International (CC BY 4.0), which allows other people to freely distribute the published work with a mandatory reference to the authors of the original work and the first publication of the work in this journal.By submitting a manuscript to the editorial office of the Journal ‘Morphologia’ authors agree to transfer the rights to protect and use the manuscript (all supplemental materials, particularly protected objects such as photos, drawings, diagrams, tables, etc.), including the reproduction in the press and distribution via the Internet; translation of the manuscript into any language; export and import of journal copies with the Authors’ article in order to make it available for public. Authors convey the rights mentioned above to the editorial office without any temporal or territorial limitation all over the world.
The Authors guarantee that they have the exclusive rights to use the material transferred to editorial office. Editors are not responsible to third parties for contraventions of warranty given by the Authors. The considered rights are transferred to the editorial office since the moment when the current issue is signed for publishing. Reproduction of materials published in the Journal by other individuals and legal entities is possible only with the consent of Editorial office, with the obligatory indication of the full bibliographic reference of the primary publication. The Authors reserve the right to use the published material, its fragments and parts for teaching materials, oral presentations, dissertation thesis prepararion with obligatory bibliographic citation of the original paper. Electron copy of the published article, downloaded from official journal web-site in .pdf format may be put by authors on the official web-site of their institutions, any other official resources with open access.
