Experimental chronic periodontitis morphogenesis.
DOI:
https://doi.org/10.26641/1997-9665.2011.1.38-41Keywords:
periodontium, periodontitis, experimental modelAbstract
Morphogenesis of periodontium tissue in a model of chronic periodontitis was studied. Adult Wistar rats were used in a model; chronic periodontitis was developed through mastication-related loading decrease. Histological assessment of periodontium tissue was conducted at Days 7, 14, 21 and 30. It was demonstrated that dystrophic tissue changes prevail over the inflammatory one in this particular experimental model. The structural elements of periodontium were involved into the pathologic process in the following sequence: gingival mucosa connective tissue – Day 7, gingival epithelium – Day 14; periodontium of the tooth-gingival connection area – Day 21; bone tissue of the alveolar process of the jaw – Days 21-30. Inflammation was manifested at Day 30, only in areas of tooth-gingival connection.
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