Morphofunctional state of tooth tissue of rats obtained when keeping to hypercalorium diet during pregnancy.
DOI:
https://doi.org/10.26641/1997-9665.2018.3.116-122Keywords:
overfeeding, teeth, ratsAbstract
Background. It is known that the prevalence of caries among the child population of Ukraine is growing every year. Objective: study the influence of the hypercaloric diet of pregnant rats on the morphofunctional tooth state of their offspring. As part of the study, an experiment was conducted on rats of WAG/G Sto population in modeling excess weight. The material for the morphological study was the incisor tooth of the mother rats’ upper jaw, their one- and two-month offspring, studied with the help of histological and morphometric methods. Results. With the hypercaloric diet, in general, there were no signs of dyspoiesis of structural and functional components of the maxillary incisor in comparison with rats that were in the standard conditions of the vivarium. Morphological changes in mono- and bi-monthly rat offspring are of the same type in the form of discirculatory changes in the tooth pulp, dystrophic changes in odontoblast and density decrease. In the dentin, focal dystrophic changes, loci of hyper- and hypocalcinosis with ratio distortion between predentine and dentin are noted. Dystrophic changes occur in adamantoblast population, and the adamantoblast density increases. Enamel and cement are characterized by uneven mineralization, focal dystrophic changes. Moreover, two-month rats have collagenogenesis hardening in hard tissues and tooth pulp. Conclusion.It was found that with the hypercaloric diet of mothers of rats, one-and two-month offspring exhibit morphofunctional changes that may lead to the development of pathologies of hard teeth and periodontium in the future.
References
- Zadorozhna IV. [Indices features of mineral density of bone tissue in children with different intensity of teeth caries]. Problemy osteolohiyi. 2016;2:15-21. Ukrainian.
- Yakubova ІІ. [Introduction of the scheme of dispensary of pregnant women in the dentist-the first step to maintaining the dental health of the mother and his formation in the child]. Novunu stomatolohii. 2012;(2):56-9. Ukrainian.
- Yakubova ІІ, Yumanovska LV, Kaskova LF. [Morphological changes of rudiment of teeth in embryos of mice under the influence of cholesterol]. Svit medicini ta biologii. 2012;(1):182-5. Ukrainian.
- Kirsanova LА, author. [Balanced feed: for pregnant and feeding]. Moscow: Centrpoligraf; 2007. 155 p. Russian.
- Kuzminaа VА. [Sanitary education of pregnant women in relation to hygiene of the oral cavity as an important link in antenatal prophylaxis of caries of teeth]. Novunu stomatolohii. 2016;(4):49-55. Ukrainian.
- Maltseva NА. [Features of the first trimester of pregnancy in women with a disorder of fat metabolism]. Author's dissertation for obtaining a scientific Ph.D degree. Moscow; 2008. Russian.
- Homenko LА, Chaikovski YB, Savichuk АV, authors. [Therapeutic stomatology of child's age]. Kyiv: Kniga plys; 2007. 816 p. Russian.
- Matasar ІТ. [Hygienic assessment of the nutrition of the ablebodied population in modern environmental conditions]. Author's abstract dissertation for obtaining a doctor's degree in medical sciences. Kyiv: National medical university named. О. О. Bohomoltsa; 2001. 40 p. Russian.
- Atramentova LА, Utevskaya ОМ, authors. [Statistical methods in biology]. Horlovka: Líkhtar; 2008. 248 p. Russian.
- Lapach SN, Chubenko АВ, Babich PN, authors. [Statistical methods in medical biological researches with the use of Exсel]. Kyiv: MORION; 2001. 408 p. Russian.
- Nikolaeva ОV, Kovaltsova МV, Yevtushenko ТG, inventors; Kharkiv national medical university, assignee. The method of overweight modeling. Ukraine patent UA 80979. 2013 June 10. Ukrainian.
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