Subacute de Quervain's thyroiditis: clinical and pathomorphological features of patients operated on thyroid gland.
DOI:
https://doi.org/10.26641/1997-9665.2018.3.99-104Keywords:
Subacute de Quervain's thyroiditi, thyroid glandAbstract
Background. An annual increase in the number of patients with endocrine pathology is observed in Ukraine. SubacutedeQuervain's thyroiditis is a rare inflammatory disease of thyroid gland of viral etiology which on average occurs in 3 - 6% of cases among all thyroid pathology. Objective – to study clinical and pathomorphological features of Subacute de Quervain's thyroiditis of patients operated on thyroid gland in the last ten years. Меthods. Analysis of archival data results of pathohistological reports on the patients operated on thyroid gland in Lviv Regional Clinical Hospital in 2006-2015 and medical histories with diagnosed cases of Subacute de Quervain's thyroiditis was conducted. In ten years’ time 5587 cases of patients operated on thyroid gland pathology have been revealed, among them 17 cases of Subacute de Quervain's thyroiditis which is 0,3% from all thyroid diseases. There were only women among the patients and their average age was 56. Results. While studying the medical histories it was revealed that the most frequent women’s complaints were the following: feeling of a foreign body in the neck area, discomfort when swallowing, bulging on the front of the neck, dyspnea, general weakness. Subacute de Quervain's thyroiditis was not diagnosed clinically in any case, and in one third of the cases there was a suspicion of malignant thyroid tumor. Pathoanatomical diagnosis in half of the cases was combined and often Subacute de Quervain's thyroiditis was combined with a multi-nodule colloid goiter. Conclusion. Subacute de Quervain's thyroiditis is a rare pathology of thyroid gland without sufficiently characteristic pathognomonic signs that makes clinical diagnostics rather difficult. Thoroughly collected anamnesis and conducting of appropriate laboratory tests including ultrasonic diagnostics of thyroid gland help to diagnose Subacute de Quervain's thyroiditis.References
- Larin OS. [Analysis of work of the endocrinology service of Ukraine in 1010 and the prospects for the development of medical care of patients with endocrine pathology]. International endocrinology journal. 2011;35(3):10-8. Ukrainian.
- Alfadda AA, Sallam RM, Elawad GE, Aldhukair H, Alyahya MM. Subacute thyroiditis: Clinical presentation and long term outcome. Int J Endocrinol. 2014;2014:794-943.
- Oláh R, Hajós P, Soós Z, Winkler G. De Quervain thyroiditis. Corner points of the diagnosis. 2014;155:676-80.
- Frates MC, Marqusee E, Benson CB, Alexander EK. Subacute Granulomatous (de Quervain) thyroiditis. Grayscale and color Doppler sonographic characteristics. J Ultrasound Med. 2013;32:505–11.
- [Subacute thyroiditis (de Quervain's thyroiditis)]. Available from: http://www.dovidnyk.org/dir/2/5/50.html. – (date: 03.08.2018). Ukrainian.
- Bindra A, Braunstein GD, Cedars-Sinai Medical Center. Thyroiditis. American Family Physician. 2006;73(10):1769–76.
- Fatourechi V, Aniszewski JP, Guiti Z, Fatourechi E, Atkinson EJ, Jacobsen SJ. Clinical Features and Outcome of Subacute Thyroiditis in an Incidence Cohort: Olmsted County, Minnesota, Study. The Journal of Clinical Endocrinology & Metabolism. 2003;88(5):2100–5. doi:http://dx.doi.org/10.1210/jc.2002-021799.
- Vural C, Paksoy N, Gök ND, Yazal K. Subacute granulomatous (De Quervain's) thyroiditis: Fine-needle aspiration cytology and ultrasonographic characteristics of 21 cases. Cyto Journal. 2015;12:9.
- Bhadauria RS, Nema SK, Kumar P. De Quervain's Thyroiditis. Medical Journal Armed Forces India. 2003;59(4):347–8.
- Cappelli C, Pirola I, Gandossi E, Formenti AM, Agosti B, Castellano M. Ultrasound findings of subacute thyroiditis: A single institution retrospective review. Acta Radiol. 2014;55:429-33.
- Omori N, Omori K, Takano K. Association of the ultrasonographic findings of subacute thyroiditis with thyroid pain and laboratory findings. Endocr J. 2008;55:583-8.
- Mordes DA, Brachtel EF. Cytopathology of subacute thyroiditis. Diagn Cytopathol. 2012;40:433-4.
- Duininck TM, Heerden JA, Fatourechi V, Curlee KJ, Farley DR, Thompson GB, Grant CS, Lloyd RV. De Quevain's Thyroiditis: Surgical Experience. Endocrine Practice. 2002;8(4):255–8. https://doi.org/10.4158/EP.8.4.255.
Downloads
How to Cite
Omelyash, U. V. (2018). Subacute de Quervain’s thyroiditis: clinical and pathomorphological features of patients operated on thyroid gland. Морфологія / Morphologia / Morfologìâ, 12(3), 99–104. https://doi.org/10.26641/1997-9665.2018.3.99-104
Issue
Section
Статті
License
Copyright (c) 2018 Morphologia

This work is licensed under a Creative Commons Attribution 4.0 International License.
The authors reserve the right to authorship of their work and transfer to the Journal the right to the first publication of this work under the terms of a license Creative commons Attribution 4.0 International (CC BY 4.0), which allows other people to freely distribute the published work with a mandatory reference to the authors of the original work and the first publication of the work in this journal.By submitting a manuscript to the editorial office of the Journal ‘Morphologia’ authors agree to transfer the rights to protect and use the manuscript (all supplemental materials, particularly protected objects such as photos, drawings, diagrams, tables, etc.), including the reproduction in the press and distribution via the Internet; translation of the manuscript into any language; export and import of journal copies with the Authors’ article in order to make it available for public. Authors convey the rights mentioned above to the editorial office without any temporal or territorial limitation all over the world.
The Authors guarantee that they have the exclusive rights to use the material transferred to editorial office. Editors are not responsible to third parties for contraventions of warranty given by the Authors. The considered rights are transferred to the editorial office since the moment when the current issue is signed for publishing. Reproduction of materials published in the Journal by other individuals and legal entities is possible only with the consent of Editorial office, with the obligatory indication of the full bibliographic reference of the primary publication. The Authors reserve the right to use the published material, its fragments and parts for teaching materials, oral presentations, dissertation thesis prepararion with obligatory bibliographic citation of the original paper. Electron copy of the published article, downloaded from official journal web-site in .pdf format may be put by authors on the official web-site of their institutions, any other official resources with open access.
