Dynamics of postoperative period after the automyelotransplantation in patients with chronic critical lower limb ischemia.

Authors

  • M. F. Dryuk A.A.Shalimov Institute of Surgery and Transplantology of the Academy of Medical Sciences of Ukraine, Ukraine
  • V. M. Shkuropat Dnipropetrovsk City Clinical Hospital №4, Ukraine

DOI:

https://doi.org/10.26641/1997-9665.2010.4.24-30

Keywords:

lower limb ischemia, revascularization, automyelotransplantation, postoperative period

Abstract

The aim of the current research was to determine the effectiveness of indirect and composite revascularization in patients of various ages with chronic lower limb ischemia of the III degree. Bone marrow autotransplantation into the anterior group of shin muscles was performed on 62 patients to stimulate vasculogenesis. 59 patients had a composite revascularization of the distal portion of the limb – a plastic operation on the arteries of shin and simultaneous indirect revascularization. The investigation was carried out on age groups: I – 34 years and younger; II – 35-59 years; III – 60-74 years; IV – 75 years and older. All patients before surgery and within 2 years after conducting determination of the maximum distance of walking and walking distance without pain and ultrasound doppler study identifying ankle-brachial index ("Sonos-1000 HP,Hewlett-Packard,USA). Studies have shown that the indirect revascularization using bone marrow aspirate autotransplantation dramatically affect the dynamics of of the maximum distance of walking and walking distance without pain and ankle-brachial index in the immediate postoperative period, however, requires stable normalization of these characteristics in patients under the age of 75 years over the next two years after the intervention. The stimulation of synthetic activity takes place to the utmost when automyelotransplantation is performed on the patients of young and mature age, to a lesser degree when patients are of middle age. In the patients of 75 years and older the effect of bone marrow aspirate during the indirect or composite revascularization is not revealed.

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How to Cite

Dryuk, M. F., & Shkuropat, V. M. (2010). Dynamics of postoperative period after the automyelotransplantation in patients with chronic critical lower limb ischemia. Морфологія / Morphologia / Morfologìâ, 4(4), 24–30. https://doi.org/10.26641/1997-9665.2010.4.24-30

Issue

Vol. 4 No. 4 (2010)

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