Tissue state of anterior abdominal wall in rats after implantation of alloplastic material, processed with collagen, in the abdominal cavity and in contact with hollow organs.

Authors

  • L. S. Belyanskyi A.A.Shalimov Institute of Surgery and Transplantology of the Academy of Medical Sciences of Ukraine, Ukraine
  • O. V. Svisenko Special Medical and Sanitary Department № 6, Dnepropetrovsk, Ukraine

DOI:

https://doi.org/10.26641/1997-9665.2010.4.13-18

Keywords:

polypropylene mesh, collagen, transabdominal fixation, tissue reaction

Abstract

A research purpose was to investigate the tissue reactions on implantation of polypropylene mesh, processed with collagen, after the plastic of experimental defect at rats at intraperitoneal localization of prosthesis in contact with hollow organs. Research was performed in two experimental groups. Group 1 – at 27 rats an experimental defect of of anterior abdominal wall of size 3 cm, with further transabdominal fixation of the polypropylene mesh of size 1×1,5 cm on parietal peritoneum in contact with hollow organs, was performed. Group 2 – at 28 rats at analogous conditions the intraperitoneal fixation of polypropylene mesh, processed with collagen, was performed. Morphological analysis of scar tissue formation phases in rats in the implantation region in the abdominal cavity and contact with hollow organs from the data of cellular and fiber structures stereological characteristics of connective tissue with hemodynamic characteristics shows substantial benefits of use of polypropylene mesh, processed with collagen, during 4 weeks after experimental hernioplasty.

References

  1. Автандилов Г. Г. Системная стереометрия в изучении патологического процесса / Г. Г. Автандилов, Н. И. Яблучанский, В. Г. Губенко. – М. : Медицина, 1981. – 192 с.
  2. Ромейс Б. Микроскопическая техника: [Пер. с нем] / Б. Ромейс. – М. : Изд-во иностр. литературы, 1953. – 718 с.
  3. Твердохлеб И. В. Прикладная биометрия для морфолога / И. В. Твердохлеб, И. С. Шпонька, М. А. Машталир. – Днепропетровск : Пороги, 1996. – 226 с.
  4. Шалимов С. А. Руководство по экспериментальной хирургии / С. А. Шалимов, А. П. Радзиховский, Л. В. Кейсевич. - М. : Медицина, 1989. - 272 с.
  5. Экспериментальное обоснование применения новых поливинилиденфторидных эндопротезов с карбиновым покрытием для герниопластики / А. И. Бежин, А. А. Должиков, В. А. Жуковский, Р. В. Плотников // Вестн. новых медицинских технологий. – 2007. - Т. XIV, № 1. – С. 99–101.
  6. Antibacterial activity of triclosan chitosan coated graft on hernia graft infection model / A. Cakmak, Y Cirpanli, E. Bilensoy [et al.] // Int. J. Pharm. – 2009. – Vol. 381, № 2. – P. 214-219.
  7. Brown C. N. Which mesh for hernia repair? / C. N. Brown, J. G. Finch // Ann. R. Coll. Surg. Engl. – 2010. – Vol. 92, № 4. – P. 272-278.
  8. Comparison of recurrence with lightweight composite polypropylene mesh and heavyweight mesh in laparoscopic totally extraperitoneal inguinal hernia repair: an audit of 1,232 repairs / D. Akolekar, S. Kumar, L. R. Khan [et al.] // Hernia. – 2008. –Vol. 12, № 1. – P. 39-43.
  9. Eriksen J. R. Choice of mesh for laparoscopic ventral hernia repair / J. R. Eriksen, I. Gögenur, J. Rosenberg // Hernia. – 2007. – Vol. 11, № 6. – P. 481-492.
  10. Evaluation of lightweight titanium-coated polypropylene mesh (TiMesh) for laparoscopic repair of large hiatal hernias // E. J. Hazebroek, A. Ng, D. H. Yong [et al.] // Surg Endosc. – 2008. – Vol. 22, № 11. – P. 2428-2432.
  11. Saberski E. R. Anisotropic evaluation of synthetic surgical meshes // E. R Saberski, S. B. Orenstein, Y. W. Novitsky // Hernia. – 2010. – Vol. 30. – P. 423-431.
  12. Use of human acellular dermal matrix for hernia repair: friend or foe? / R. Candage, K. Jones, F. A. Luchette [et al.] // Surgery. – 2008. – Vol. 144, № 4. – P. 703-709.

How to Cite

Belyanskyi, L. S., & Svisenko, O. V. (2010). Tissue state of anterior abdominal wall in rats after implantation of alloplastic material, processed with collagen, in the abdominal cavity and in contact with hollow organs. Морфологія / Morphologia / Morfologìâ, 4(4), 13–18. https://doi.org/10.26641/1997-9665.2010.4.13-18

Issue

Section

Статті