Tissue state of anterior abdominal wall in rats after implantation of alloplastic material, processed with collagen, in the abdominal cavity and in contact with hollow organs.
DOI:
https://doi.org/10.26641/1997-9665.2010.4.13-18Keywords:
polypropylene mesh, collagen, transabdominal fixation, tissue reactionAbstract
A research purpose was to investigate the tissue reactions on implantation of polypropylene mesh, processed with collagen, after the plastic of experimental defect at rats at intraperitoneal localization of prosthesis in contact with hollow organs. Research was performed in two experimental groups. Group 1 – at 27 rats an experimental defect of of anterior abdominal wall of size 3 cm, with further transabdominal fixation of the polypropylene mesh of size 1×1,5 cm on parietal peritoneum in contact with hollow organs, was performed. Group 2 – at 28 rats at analogous conditions the intraperitoneal fixation of polypropylene mesh, processed with collagen, was performed. Morphological analysis of scar tissue formation phases in rats in the implantation region in the abdominal cavity and contact with hollow organs from the data of cellular and fiber structures stereological characteristics of connective tissue with hemodynamic characteristics shows substantial benefits of use of polypropylene mesh, processed with collagen, during 4 weeks after experimental hernioplasty.
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