Optimization and validation of algorithm of histologic investigation of cone biopsy of cervix uteri.

Authors

  • O. V. Lukyanchuk Одесский национальный медицинский университет, Ukraine
  • L. G. Rosha Одесский национальный медицинский университет, Ukraine

DOI:

https://doi.org/10.26641/1997-9665.2014.1.109-112

Keywords:

cervix uteri, carcinoma of cervix uteri, cervical intraepithelial neoplasia, cone biopsy

Abstract

Backgrund. Adequate treatment of patients with cervical cancer remains an urgent problem of modern cancer care. In the study protocol of College of American Pathologists the algorithm of summary formation in cases of invasive cervical cancer is described in details, but there is no algorithm for the material collection. Objective. The purpose of the study was to optimize and improve the quality of histologic investigation of cervix uteri preparations. Methods. An algorithm for the pathomorphological investigation of conus bioptates of cervix uteri was created. It was introduced into the work of pathologic anatomy department of the Center of Reconstructive and Reparative Medicine (Univercity Clinic) of Odessa National Medical University. 40 macropreparations of conus bioptates of cervix uteri with cervical intraepithelial neoplasia of 2nd and 3rd stage and microinvasive carcinoma were studied. Results. Unified investigation of cone biopsy of cervix uteri guarantees precise diagnostics of neoplasia of cervix uteri, and also controls the quality of conization of cervix uteri. Investigation of consultation material from other departments of pathologic anatomy proves that introduction of such algorithms is not a material for discussion, but a necessity. Conclusion. Modern pathologic anatomy service requires the implementation of the protocols for investigation of cone biopsy of cervix uteri. The introduced protocol corresponds to all the requirements of oncomorphology, involves all stages of the investigation, and can be recommended for use in the work of pathologic anatomy departments.

References

  1. Kondrikov NI, author. [Pathology of uterus: morphology, physiology, diagnostics, basic therapy: Illustrated guide]. Moscow: Practical Medicine; 2008. 334 p. Russian.
  2. Andreyeva YuYu, Frank GA, editors. [Tumours of cervix uteri. Morphologic diagnostics and genetics. Guide for doctors]. Moscow: Practical Medicine; 2012. 115 p. Russian.
  3. [On development and evaluation of pathologic anatomy service in Ukraine]. Order of Ministry of Health of Ukraine; 1992 May 12;81. Ukrainian.
  4. Allen DC. Histopathology reporting: guide-lines for surgical cancer. 2nd ed. Springer; 2006. 486 p.
  5. Dallenbach-Hellweg G, von Knebel Doeberitz M, Trunk MJ. Color atlas of histopathology of the cervix uteri. Springer, 2005. 196 p.
  6. Kalof AN, Dadmanesh F, Longacre TA, Nucci MR, Oliva E, Otis CN, Cooper K, Collefe of American Pathologists. Protocol for the examination of specimens from patients with carcinoma of the uterine cervix. CAP: 2013 Dec. 19 p. Available from: http://www.cap.org/apps/docs/committees/cancer/cancer_protocols/2013/Cervix_13protocol_3210.pdf
  7. Kurman RJ, Carcangiu ML, Herrington CS, Young RH. WHO classification of tumours of the female reproductive organs. 4th ed. 2014. 307 p.

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How to Cite

Lukyanchuk, O. V., & Rosha, L. G. (2014). Optimization and validation of algorithm of histologic investigation of cone biopsy of cervix uteri. Морфологія / Morphologia / Morfologìâ, 8(1), 109–112. https://doi.org/10.26641/1997-9665.2014.1.109-112

Issue

Vol. 8 No. 1 (2014)

Section

Статті

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