Cortisol and pregnenolone as diagnostic criteria for evaluating the duration of dying of a person at the early stages of antemortem period.

Authors

  • A. M. Bilyakov Національний медичний університет імені О.О.Богомольця, м. Київ, Ukraine

DOI:

https://doi.org/10.26641/1997-9665.2012.4.18-21

Keywords:

pregnenolone, cholesterol, cortisol, trauma, steroidogenesis

Abstract

The content of cortisol and its precoursor pregnenolone in adrenal tissue was evaluated with the purpose of determining the duration of dying of a human being influenced by a lethal traumatic factor. It is shown that pregnenolone as an intermediate component of steroidogenesis is not identified in adrenal tissue of the persons who died as a result of a traumatic factor influence. The amount of cortisol in adrenal tissue differs depending on the duration of dying of a person and can be used as a diagnostic criterion for evaluating the duration of dying of the person at an early stage of antemortem period.

References

  1. Біляков А. М. Програмна обробка результатів тонкошарової хроматографії / Біляков А. М. // Актуальні питання судово-медичної науки, освіти і практики : матеріали всеукр. конф. – Алушта, 2012. – С. 92-94.
  2. Динамика участия гипофиза, эпифиза и надпочечников в организации стресс-реакции при смертельной травме / А. Ф. Яковцова, Г. И. Губина-Вакулик, В. Д. Марковський, И. В. Сорокина // Патологія. – 2005. –Т. 2, № 3. – С. 35.
  3. Пащенко Ю. В. Морфофункциональные критерии продолжительности жизни пострадавшего после механической травмы / Пащенко Ю. В. // Роль сучасних методів діагностики в лікуванні та реабілітації хворих : матеріали конф. Харків. обл. клін. лікарні. – Харків., 2004. – С. 50-51.
  4. Peter M. Transcription factors as regulators of steroidogenic P-450 enzymes / M. Peter, J. M. Dubuis // Eur. J. Clin. Investig. – 2000. – Vol. 30, № 3. – P. 14-20.

Downloads

How to Cite

Bilyakov, A. M. (2012). Cortisol and pregnenolone as diagnostic criteria for evaluating the duration of dying of a person at the early stages of antemortem period. Морфологія / Morphologia / Morfologìâ, 6(4), 18–21. https://doi.org/10.26641/1997-9665.2012.4.18-21

Issue

Vol. 6 No. 4 (2012)

Section

Статті

License

Copyright (c) 2018 Morphologia

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

 The authors reserve the right to authorship of their work and transfer to the Journal the right to the first publication of this work under the terms of a license Creative commons Attribution 4.0 International (CC BY 4.0), which allows other people to freely distribute the published work with a mandatory reference to the authors of the original work and the first publication of the work in this journal.
        By submitting a manuscript to the editorial office of the Journal ‘Morphologia’ authors agree to transfer the rights to protect and use the manuscript (all supplemental materials, particularly protected objects such as photos, drawings, diagrams, tables, etc.), including the reproduction in the press and distribution via the Internet; translation of the manuscript into any language; export and import of journal copies with the Authors’ article in order to make it available for public. Authors convey the rights mentioned above to the editorial office without any temporal or territorial limitation all over the world. 
        The Authors guarantee that they have the exclusive rights to use the material transferred to editorial office. Editors are not responsible to third parties for contraventions of warranty given by the Authors. The considered rights are transferred to the editorial office since the moment when the current issue is signed for publishing. Reproduction of materials published in the Journal by other individuals and legal entities is possible only with the consent of Editorial office, with the obligatory indication of the full bibliographic reference of the primary publication. The Authors reserve the right to use the published material, its fragments and parts for teaching materials, oral presentations, dissertation thesis prepararion with obligatory bibliographic citation of the original paper. Electron copy of the published article, downloaded from official journal web-site in .pdf format may be put by authors on the official web-site of their institutions, any other official resources with open access.