Comparison of physiological and morphological parameters of the parathyroid glands in the age aspect.

Authors

  • O. R. Dzhura Львівський національний медичний університет імені Данила Галицького, Ukraine

DOI:

https://doi.org/10.26641/1997-9665.2013.2.41-46

Keywords:

parathyroid glands, parathormone, morphometry, histochemistry, hyperparathyroidism

Abstract

The content of parathormone in blood plasma of 604 persons with previously identified elevated general calcium level in blood has been studied. The amount of appeals from females has three times exceeded the males’ ones. All the results have been divided into six groups according to the age of people under study: the first group (from 1 month to 14 years old), the second group (15-29 years old), the third group (30-44 years old), the fourth group (45-59 years old), the fifth group (60-74 years old), and the sixth group (75-90 years old). 105 cases of hyperparathyroidism which make up 17.38% have been registered. The division according to the gender character has pointed out the females’ dominance – 10.92%. The significant increase of hyperthyroidism in age aspect has been marked; in persons of the third-fifth groups hyperthyroidism has been indicated in every fifth person under study, and in the sixth group – in every fourth person under study. The highest percent of persons with low indexes of parathormone has been detected in the first age group. In morphological studying of parathyroid glands the gradual decrease of the principal parathyrocytes’ amount along with the enlargement of their nuclei’ diameter with simultaneous insignificant increase of the nucleic acid content in women of older age groups.

References

  1. Горальський Л. П. Основи гістологічної техніки і морфофункціональні методи дослідження у нормі та при патології / Л. П. Горальський, В. Т. Хомич, О. І. Кононський. – Житомир : Полісся, 2005. – 288 с.
  2. Дефіцит та недостатність відаміну D у жителів України / В. В. Поворознюк, Н. І. Балацька, В. Я. Муц, О. А. Вдовіна // Боль. Суставы. Позвоночник. – 2011. - № 4. – С. 5-13.
  3. Коваленко В. М. Рекомендації з діагностики, профілактики та лікування системного остеопорозу у жінок в постменопаузальному періоді / В. М. Коваленко, В. В. Поворознюк. – Київ, 2010. – С. 8-45.
  4. Луцик А. Д. Лектины в гистохимии / А. Д. Луцик, Е. С. Детюк, М. Д. Луцик : [под ред. Е. Н. Панасюка]. – Львов : Вища школа, 1989. – 144 с.
  5. Павлов А. В. Клеточное обновление в паренхиме и строме околощитовидных желез / А. В. Павлов, В. В. Запрягаев //Арх. анат., гистол. и эмбриол. – 1989. – Т. 96, № 1. – С. 78-82.
  6. Поворознюк В. В. Менопауза и остеопороз / В. В. Поворознюк, Н. В. Григорьева // Doctor. – 2002. - № 5. – С. 50-55.
  7. Поворознюк В. В. Сучасні принципи діагностики та лікування захворювань кістково-м’язової системи в людей різного віку / за ред. В. В. Поворознюка. – Київ : Карбон-Сервіс. – 2008. – 220с.
  8. Рапопорт С. И. Остеопороз как проблема в клинике внутренних болезней / С. И. Рапопорт, Н. К. Малиновская, Л. А. Вознесенская // Клин. медицина. – 2000. – Т. 78, № 4. – С. 49-53.
  9. Рибаков С. Й. Синдромні характеристики первинного гіперпаратиреозу / С. Й. Рибаков, І. В. Комісаренко, А. М. Кваченюк // Ендокринологія. – 2002. – Т. 7, № 1. – С. 62-68.
  10. Риггс Б. Л. Остеопороз / Б. Л. Риггс, Дж. III Мелтон: [пер. с англ. И. Скрипникова, Н. Бунчук, Т. Баркова]. – М. : БИНОМ, 2000. – 560 с.
  11. Bilyy R. Search of novel cell surface markers of apoptotic cells // R. Bilyy, R. Stoika // Autoimmunity. – 2007. – Vol. 40, № 4. – P. 249-253.
  12. Cummings S. K. Clinical use of densitometry / S. K. Cummings, D. Bates, D. M. Black // JAMA. – 2002. – Vol. 288, № 15. – P. 1889-1897.
  13. Holick M. F. Evaluation, treatment, and prevention of vitamin D deficiency: an endocrine society clinical practice / M. F. Holick, N. C. Binkley, H. A. Bischoff-Ferrari // J. Clin. Endocrinol. Metab. – 2011. – Vol. 96, № 7. – P. 1911-913.
  14. Igbal M. M. Osteoporosis: epidemiology, diagnosis and treatment // South Med. J. – 2000. – Vol. 93, № 1. – P. 2-18.
  15. Primary hyperparathyroidism: referral patterns and outcomes of surgery / R. S. Flint, C. R. Harmann, J. Carter, G. Snyman // ANZ Journal of Surgery. – 2002. – Vol. 72, № 3. – P. 200-209.
  16. Sharon N. Lectins: carbohydrate-specific reagents and biological recognition molecules / N. Sharon // J. Biol. Chem. – 2007. – Vol. 282. – P. 2753–2764.
  17. Vitamin D deficiency and insufficiency among Ukrainian population / V. V. Povoroznyuk, N. I. Balatska, V. Y. Muts [et al.] // Standardy medyczne. Pediatria. – 2012. – Vol. 5, № 9. – P. 584-589.

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How to Cite

Dzhura, O. R. (2013). Comparison of physiological and morphological parameters of the parathyroid glands in the age aspect. Морфологія / Morphologia / Morfologìâ, 7(2), 41–46. https://doi.org/10.26641/1997-9665.2013.2.41-46

Issue

Vol. 7 No. 2 (2013)

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