Clinical and morphological features of carcinoid tumors.

Authors

  • V. D. Markovskiy Харківський національний медичний університет, Ukraine
  • V. V. Zaharenko КЗОЗ «Обласна клінічна лікарня – центр екстреної медичної допомоги і медицини катастроф», Харків, Ukraine
  • I. V. Sorokina Харківський національний медичний університет, Ukraine
  • O. N. Pliten Харківський національний медичний університет КЗОЗ «Обласна клінічна лікарня – центр екстреної медичної допомоги і медицини катастроф», Харків, Ukraine
  • M. S. Myroshnychenko Харківський національний медичний університет КЗОЗ «Обласна клінічна лікарня – центр екстреної медичної допомоги і медицини катастроф», Харків, Ukraine
  • A. S. Shapkin Харківський національний медичний університет КЗОЗ «Обласна клінічна лікарня – центр екстреної медичної допомоги і медицини катастроф», Харків, Ukraine

DOI:

https://doi.org/10.26641/1997-9665.2013.3.10-15

Keywords:

carcinoid tumor, clinical and morphological features

Abstract

Carcinoid tumors are rare tumors in practice of doctors of various specialties. These tumors are histological findings in the most cases because they are masked by clinical and morphological features of neoplastic and non-neoplastic diseases. In some cases, carcinoid tumors generally remain undetected due to lack of awareness among physicians about clinical and morphological characteristics of such disease. Believe it is important to recall the features of this tumor. The article presents the literature data and own observations from practice of carcinoid tumor of rare localization: bronchus, colon, mammary gland. In all three of our observations, where cancer was clinically suspected, the diagnosis of carcinoid tumor was made only after histology. Only complications have led to the surgical intervention, and, unfortunately, the diagnosis of carcinoid was made after death. In the latter case carcinoid, most likely played an important role in thanatogenesis. Unification of efforts of doctors in various fields will make progress in the diagnosis and treatment of carcinoid tumors, extending the lives of patients suffering from this disorder.

References

  1. Фролова-Романюк Э. Ю. Карциноид: особенности клинической картины / Э. Ю. Фролова-Романюк // Здоров’я України. – 2010. – №1. – С. 48–49.
  2. Frolova-Romaniuk EYu. [Carcinoid: peculiarities of clinical presentation] Zdorovya Ukrayiny [Health of Ukraine]. 2010 Feb;(1):48-9. Russian.
  3. Буриев И. М. Карциноидные опухоли поджелудочной железы / И. М. Буриев, В. В. Цвиркун, А. Н. Лебедева [и др.] // Анналы хирургической гепатологии. − 1997. − Т. 2. − С. 74–81.
  4. Buriev IM, Tsvirkun VV, Lebedeva AN, Savvina TV, Klintsevich GT, Karmasanovsky GG, Karelin AA. [Carcinoid tumors of the Pancreas]. Annaly khirurgicheskoy gepatologii. 1997; 2: 74-81. Russian.
  5. Тер-Ованесов М. Д. Карциноидные опухоли торакальной локализации – современное состояние / М. Д. Тер-Ованесов, Б. Е. Полоцкий // Практическая онкология. – 2005. – Т. 6, № 4. – С. 220–226.
  6. Ter-Ovanesov MD, Polotskiy BYe. [Carcinoid tumors of thoracic localization – the modern state of the problem]. Prakticheskaya onkologiya. 2005;6(4):220-6. Russian.
  7. Lubarsch O. Ueber den primären Krebs des Ileum, nebst Bemerkungen ber das gleichzeitige Vorkommen von Krebs und Tuberkolose / O. Lubarsch // Virchows Arch. – 1888. – Vol. 111. – P. 280–317.
  8. Lubarsch O. Uber den primaren Krebs des ileum nebst bemerkunger uber das gleichzeitige vorkommen von Krebs und tuberculose. Virchows Arch Pathol. 1888; 111: 280-317. German. DOI:10.1007/BF01966242
  9. Oberndorfer S. Karzinoide Tumoren des Dünndarms / S. Oberndorfer // Frankf. Z. Pathol. – 1907. – Vol. 1. – P. 425–429.
  10. Oberndorfer S. Karzinoide Tumoren des Dunndarms. Frankf Z Pathol 1907;1:425-9. German.
  11. Головин Д. И. Инкреторные гранулоцитомы (апудомы) / Д. И. Головин, O. K. Хмельницкий. − Л. : Медицина, 1983. – 152 с.
  12. Golovin DI, Khmelnitskiy OK, Nikonov AA, et al., authors; Golovin DI, Khmelnitskiy OK, editors. [Incretory granulocytomas (the apudomas): the issues of histology, histogenesis, morphological diagnosis]. Leningrad: Meditsina; 1983. 152 p. Russian.
  13. Pearse A. The diffuse neuroendocrine system and the APUD concept / A. Pearse // Med. Biol. − 1977. − Vol. 55. − P. 149–156.
  14. Pearse AG. The diffuse neuroendocrine system and the apud concept: related "endocrine" peptides in brain, intestine, pituitary, placenta, and anuran cutaneous glands. Med Biol. 1977 Jun;55(3):115-25. Cited in: PubMed; PMID: 330966.
  15. Cheng H. Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. Enteroendocrine cells / H. Cheng, C. Leblond // Amer. J. Anat. − 1974. − Vol. 141. − P. 503–520.
  16. Cheng H, Leblond CP. Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. V. Unitarian Theory of the origin of the four epithelial cell types. Am J Anat. 1974 Dec;141(4):537-61. Cited in: PubMed; PMID: 4440635.
  17. Andrew A. APUD cells, apudomas and the neural crest / A. Andrew // S. Afr. Med. J. − 1976. − Vol. 50. − P. 890-898.
  18. Andrew A. APUD cells, apudomas and the neural crest. S Afr Med J. 1976 May 29;50(23):890-8. Cited in: PubMed; PMID: 935982.
  19. Pichert C. Enterogenouss cysts of pancreas / C. Pichert //Am. J. Gastroenterol. − 1982. − Vol. 77. − P. 576.
  20. Pilcher CS, Bradley EL 3rd, Majmudar B. Enterogenous cyst of the pancreas. Am J Gastroenterol. 1982 Aug;77(8):576-7. Cited in: PubMed; PMID: 7102641.
  21. Feyrter F. Uber die peripheren endokrinen (parakrinen). Drusen des Menschen / F. Feyrter // Wien-Dusseldorf. : W. Maudrich, 1953. − P. 231.
  22. Feyrter F. Uber die peripheren endokrinen (parakrinen). Drusen des Menschen. Wien-Dusseldorf Wilhelm Maudrich Verlag; 1953. P. 231. German.
  23. Райхлин Н. Т. APUD-система (общепатологические и онкологические аспекты) / Н. Т. Райхлин, И. М. Кветной, М. А. Осадчук. − Обнинск, 1993. – 108 с.
  24. Raikhlin NT, Kvetnoy IM, Osadchuk MA. [The APUD system – general pathological and oncological aspects]. Part II. Obninsk; 1993. 108 p. Russian.
  25. Williams E. D. The classification of carcinoid tumours / E. D. Williams, M. Sandler // Lancet. – 1963. – P. 238–239.
  26. Williams ED, Sandler M. The classification of carcinoid tumours Lancet. 1963 Feb 2;1(7275):238-9. Cited in: PubMed; PMID: 14000847.
  27. Стариков В. И. Карциноидные опухоли / В. И. Стариков // Международный медицинский журнал. – 2004. – № 2. – С. 90–92.
  28. Starikov VI. [Carcinoid tumors]. International medical journal. 2004;(2): 90-92. Russian.

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How to Cite

Markovskiy, V. D., Zaharenko, V. V., Sorokina, I. V., Pliten, O. N., Myroshnychenko, M. S., & Shapkin, A. S. (2013). Clinical and morphological features of carcinoid tumors. Морфологія / Morphologia / Morfologìâ, 7(3), 10–15. https://doi.org/10.26641/1997-9665.2013.3.10-15

Issue

Vol. 7 No. 3 (2013)

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