Effectiveness of osteotropic material Easy-Graft according morphological analysis in experiment and for the assessment of life quality in patients with generalized periodontitis І severity level.

Authors

  • E. O. Dmitrieva ДЗ «Дніпропетровська медична академія МОЗ України», Ukraine

DOI:

https://doi.org/10.26641/1997-9665.2013.4.23-29

Keywords:

generalized periodontitis, bone defect, bone regeneration, EasyGraft, amorphous calcium phosphate, life quality

Abstract

Background. The theoretical basis of osteoplasty, fully supported by clinical observations, is that violations occur in periodontitis of correlation between tooth and the surrounding tissues, including the microcirculation. However, complex morphological and clinical analysis of effectiveness of the material held EasyGraft was not. Objective. The aim was experimental evaluation of tissue alterations in bone implant materials Easy-Graft® and tricalcium phosphate®, as well as determining the life quality after use in the surgical treatment of patients with generalized periodontitis І severity level. Methods. The comparative analysis a quantitative morphological estimation of regenerative processes in osteal tissue in model of osteal defect is carried out at implantation of material EasyGraft and amor­p­hous calcium phosphate at this work. It was investigated dynamics of life quality indicators at patients after used materials by specialised questionnaire OHІР-14 during 1 year. Results and Conclusion. We found out that EasyGraft and amorphous calcium phosphate undergo resorbtion and thus optimize bone regeneration. Regeneration is accompanied by decreased specific area of the particles implanted and increased integration index and specific density of trabeculae within the reaction zone. Highest intensity of these processes was ob-served in the period from 15th fill the 30th day after implantation. EasyGraft is more preferable for implantation than amorphous calcium phosphate. Adapted Ukrainian language and Russian language version of the OHIP-14 questionnaire (Oral Health Impact Profile) is valid and accurate tool for assessing the quality of life of patients with chronic generalized periodontitis by which demonstrated the influence of the intensity of inflammatory and destructive changes periodontal severity of the pathological process, the presence of complete occlusion and methods of correction applied to the subjective perception of quality of life. The use of material EasyGraft compared with tricalcium phosphate improves the life quality of patients by 18-20 %.

References

  1. Мазур І. П. Структурно-функціональний стан тканини пародонта у людей різного віку та статі / І. П. Мазур // Современная стоматология. – 2005. – № 4. – С. 48-51.
  2. Mazur IP. [Structural and functional condition of the periodontal tissues in populace of different ages and gender / IP Mazur // Sovremennaya stomatologia. 2005;4:48-51. Ukrainian.
  3. Герелюк В. І. Ультраструктура ендотеліоцитів капілярів ясен і вміст ліпопротеїдів у ясенній рідині людей при хронічному генералізованому пародонтиті / В. І. Герелюк // Укр. мед. альм. – 2000. – Т. 3, № 1. – С. 36-39.
  4. Gerelyuk VI. [The ultrastructure of endothelial cells of ash capillaries and content of lipoproteins in gingival fluid of people with chronic generalized periodontitis]. Ukr Med Alm. 2000;3(1):36-9. Ukrainian.
  5. Материнський В. В. Поріг електрозбудливості пульпи зубів різних груп в нормі та при генералізованому пародонтиті / В. В. Материнський, В. І. Герелюк // Галицький лікар. вісн. – 2005. – Т. 12, № 3. – С. 64-66.
  6. Materinsky VV, Gerelyuk VI. [The threshold electrical excitability dental pulp of different groups in norm and generalized periodontitis]. Galytskiy likarskiy visnyk. 2005;12(30:64-6. Ukrainian.
  7. Araújo A. C. Impact of periodontal disease on quality of life / A. C. Araújo, E. S. Gusmão, J. E. Batista, R. Cimões // Quintessence Int. – 2010. –Vol. 41. – № 6. – Р. 111-118.
  8. Araújo AC, Gusmão EC, Batista JE, Cimões R. Impact of periodontal disease on quality of life. Quintessence Int. 2010;41(6):111-8.
  9. Shearer D. M. Does maternal oral health predict child oral health-related quality of life in adulthood? / D. M. Shearer, W. M. Thomson, J. M. Broadbent, R. Poulton // Health Qual. Life Outcomes. – 2011. – № 9. – Р. 50.
  10. Shearer DM, Thomson WM, Broadbent JM, Poulton R. Does maternal oral health predict child oral health-related quality of life in adulthood? Health Qual Life Outcomes. 2011;9:50.
  11. Лузин В. И. Методика моделирования костного дефекта у лабораторных животных / В. И. Лузин, Д. В. Ивченко, А. А. Панкратьев [и др.] // Укр. мед. альм. – 2005. – Т. 8, № 2 (додаток). – С. 162.
  12. Luzin VI, Ivchenko DV, Pankratiev AA et al. [Methods of modeling the bone defect in laboratory animals]. Ukr Med Alm. 2005;8(2):162. Russian.
  13. European convention for the protection of vertebrate animals used for experimental and other scientific purpose: Council of Europe 18.03.1986. – Strasbourg, 1986. – 52 p.
  14. European convention for the protection of vertebrate animals used for experimental and other scientific purpose: Council of Europe 18.03.1986. Strasbourg; 1986. 52 p.
  15. Автандилов Г. Г. Медицинская морфометрия : [руководство] / Г. Г. Автандилов. - М. : Медицина, 1990. - 384 с.
  16. Avtandilov GG. Meditsinskaya morfometriya [Medical morphometry]. Moskow: Meditsina; 1990. 384 p. Russian.
  17. Sanders A. E. Impact of oral disease on quality of life in the US and Australian populations / A. E. Sanders, G. D. Slade, S. Lim, S. T. Reisine // Community Dent. Oral Epidemiol. – 2009. – № 37. – Р. 171–181.
  18. Sanders AE, Slade GD, Lim S, Reisine ST. Impact of oral disease on quality of life in the US and Australian populations. Community Dent Oral Epidemiol. 2009;37:171-81.

Downloads

How to Cite

Dmitrieva, E. O. (2013). Effectiveness of osteotropic material Easy-Graft according morphological analysis in experiment and for the assessment of life quality in patients with generalized periodontitis І severity level. Морфологія / Morphologia / Morfologìâ, 7(4), 23–29. https://doi.org/10.26641/1997-9665.2013.4.23-29

Issue

Vol. 7 No. 4 (2013)

Section

Статті

License

Copyright (c) 2018 Morphologia

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

 The authors reserve the right to authorship of their work and transfer to the Journal the right to the first publication of this work under the terms of a license Creative commons Attribution 4.0 International (CC BY 4.0), which allows other people to freely distribute the published work with a mandatory reference to the authors of the original work and the first publication of the work in this journal.
        By submitting a manuscript to the editorial office of the Journal ‘Morphologia’ authors agree to transfer the rights to protect and use the manuscript (all supplemental materials, particularly protected objects such as photos, drawings, diagrams, tables, etc.), including the reproduction in the press and distribution via the Internet; translation of the manuscript into any language; export and import of journal copies with the Authors’ article in order to make it available for public. Authors convey the rights mentioned above to the editorial office without any temporal or territorial limitation all over the world. 
        The Authors guarantee that they have the exclusive rights to use the material transferred to editorial office. Editors are not responsible to third parties for contraventions of warranty given by the Authors. The considered rights are transferred to the editorial office since the moment when the current issue is signed for publishing. Reproduction of materials published in the Journal by other individuals and legal entities is possible only with the consent of Editorial office, with the obligatory indication of the full bibliographic reference of the primary publication. The Authors reserve the right to use the published material, its fragments and parts for teaching materials, oral presentations, dissertation thesis prepararion with obligatory bibliographic citation of the original paper. Electron copy of the published article, downloaded from official journal web-site in .pdf format may be put by authors on the official web-site of their institutions, any other official resources with open access.