Relationship of electrical resistance end morphological changes thigh rats after modeling of open fracture (experimental study).

Authors

  • T. M. Pavlova Kharkiv National Medical University, Ukraine
  • M. I. Berezka Kharkiv National Medical University, Ukraine

DOI:

https://doi.org/10.26641/1997-9665.2016.2.31-39

Keywords:

bone fracture, electrical resistance, osteocytes, histological analysis

Abstract

Background. Due to the development of industry, increasing number of vehicles on the roads rate of traumatic injuries among adult population causing disability and mortality is still high in all countries of the world. Among all fractures of long bones open diaphyseal fractures ranges from 28% to 53%. Objective. To study the relationship of electrical resistance and morphological features of the femur of white male rats after modeling the open fracture. Methods. Studies were conducted on white male rats aged about 3 months. Digital multimeter UT70B was used to measure the electrical resistance of bones in experimental animals after 1 and 3 hours of experimental modeling of opened bone fracture. Histological and electron microscopic studies were performed to evaluate bone structure. Results. 1 hour after modeling an open bone fracture it was detected the presence of empty lacunae or gaps filled with detritus. 3 hours after the experiment cellular density in the first studied area was reduced 4.1 times, in the second area - 3.2 times comparing with the control. Conclusion. These histological examination and study of the electrical resistance of bone fragments after re-fracture (with or without coagulation fragments) indicate similar changes in direction of the bone. Electrical resistance after testing in the clinical setting can be used for testing the bone fragments after an open fracture to assess viability. We have developed a technique for evaluation the electrical resistance making it possible to predict the viability of bone tissue with opened diaphyseal fractures of extremities on early stages.

References

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How to Cite

Pavlova, T. M., & Berezka, M. I. (2016). Relationship of electrical resistance end morphological changes thigh rats after modeling of open fracture (experimental study). Морфологія / Morphologia / Morfologìâ, 10(2), 31–39. https://doi.org/10.26641/1997-9665.2016.2.31-39

Issue

Vol. 10 No. 2 (2016)

Section

Статті

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