Features of content and balance of toxic trace elements in hair of mothers and their premature infants.

Authors

  • I. Shkolna Sumy State University, Ukraine
  • V. Markevych Kyiv Medical University of Ukrainian association of folk medicine, Ukraine

DOI:

https://doi.org/10.26641/1997-9665.2017.2.52-57

Keywords:

toxic elements, hair, prematurity, premature birth.

Abstract

Background. Objective. The aim of the study was to investigate features of content and balance of toxic trace elements (Cr, Cd, Pb, Ni) in hair of mothers and their premature infants at different gestational ages. Methods. We have studied content of Cr, Cd, Pb, Ni in hair of 40 mothers and their newborns. The content of microelements was studied using atomic absorption spectrophotometer C-115 MI, equipped with a computer console for automatic calculation of trace elements production of HBO «Selmi» (Ukraine). Results. We have established average content and ratio of toxic elements (Cr, Cd, Pb, Ni) in hair of mothers and their premature infants at different gestational ages. Conclusions. It was established that the level of toxic trace elements were higher in the hair of women, compared to their newborn children. Indicators of chromium and nickel content in the hair of mothers which born babies at earlier gestational age were high, perhaps due to the greater exposure of metals from the environment on pregnant women. Level of Cr, Cd and Ni in hair of extremely premature babies was higher than in babies which were born at a later date. It may be possible due to improved functioning of placenta as a barrier to the micronutrients during final stages of fetal development.

References

  1. Blencowe H, Cousens S, Oestergaard MZ, Chou D, Moller AB, Narwal R, Adler A, Vera Garcia C, Rohde S, Say L, Lawn JE. National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications. Lancet. 2012 Jun 9;379(9832):2162-72. doi: 10.1016/S0140-6736(12)60820-4.
  2. Blencowe H, Cousens S, Chou D, Oestergaard M, Say L, Moller AB, Kinney M, Lawn J. Born too soon: the global epidemiology of 15 mil-lion preterm births. Reprod Health. 2013;10(1):S2. doi: 10.1186/1742-4755-10-S1-S2.
  3. Rodríguez-Barranco M, Lacasaña M, Agui-lar-Garduño C, Alguacil J, Gil F, González-Alzaga B, Rojas-García A. Association of arsenic, cadmium and manganese exposure with neurodevelopment and behavioural disorders in children: a systematic review and meta-analysis. Sci Total Environ. 2013;454-455:562-77. doi: 10.1016/j.scitotenv.2013.03.047.
  4. Starodubtseva NL, Kononikhin AS, Bugrova AE, Chagovets V, Indeykina M, Krokhina KN, Nikitina IV, Kostyukevich YI, Popov IA, Larina IM, Timofeeva LA, Frankevich VE, Ionov OV, Degtyarev DN, Nikolaev EN, Sukhikh GT. Investi-gation of urine proteome of preterm newborns with respiratory pathologies. J Proteomics. 2016;149:31-7. doi: 10.1016/j.jprot.2016.06.012.
  5. Chen TC, Priambodo R, Huang RL, Huang YH. The effective electrolytic recovery of dilute copper from industrial wastewater. Journal of Waste Management. 2013:1-6. doi:10.1155/2013/164780.
  6. Singh R, Gautam N, Mishra A, Gupta R. Heavy metals and living systems: An overview. In-dian J Pharmacol. 2011;43(3):246-53. doi: 10.4103/0253-7613.81505.
  7. Mahalakshmi M, Balakrishnan S, Indira K, Srinivasan M. Characteristic levels of heavy metals in canned tuna fish overview. Journal of Toxicology and Environmental Health Sciences. 2012;4(2):43-5. doi: 10.5897/JTEHS11.079.
  8. Jaishankar M, Tseten T, Anbalagan N, Mathew BB, Beeregowda KN. Toxicity, mechanism and health effects of some heavy metals. Interdiscip Toxicol. 2014;7(2):60-72. doi: 10.2478/intox-2014-0009.
  9. Fenton TR, Kim JH. A systematic review and meta-analysis to revise the Fenton growth chart for preterm infants. BMC Pediatrics. 2013;13(1):59. doi:10.1186/1471-2431-13-59.
  10. Esteban-Vasallo MD, Aragonés N, Pollan M, López-Abente G, Perez-Gomez B. Mercury, cadmium, and lead levels in human placenta: a systematic review. Environ Health Perspect. 2012;120(10):1369-77. doi: 10.1289/ehp.1204952.
  11. Kim YM, Chung JY, An HS, Park SY, Kim BG, Bae JW, Han M, Cho YJ, Hong YS. Biomonitoring of lead, cadmium, total mercury, and methylmercury levels in maternal blood and in um-bilical cord blood at birth in south korea. Int J Envi-ron Res Public Health. 2015;12(10):13482-93. doi: 10.3390/ijerph121013482.
  12. Das KK, Das SN, Dhundasi SA. Nickel, its adverse health effects & oxidative stress. Indian J Med Res. 2008;128(4):412-25.
  13. Stojanovic D, Nikic D. The exposure of the foetus and the breast-fed newborn of women smok-ers to carcinogenic element nickel. Facta Universitatis, Series: Medicine and Biology. 2005;12(2):89-92.
  14. Needleman H. Lead poisoning. Annual Re-view of Medicine. 2004;55:209-22. doi: 10.1146/annurev.med.55.091902.103653.
  15. Iyengar GV, Rapp A. Human placenta as a ‘dual’ biomarker for monitoring fetal and maternal environment with special reference to potentially toxic trace elements. Part 3. Toxic trace elements in placenta and placenta as a biomarker for these ele-ments. Sci Total Environ. 2001;280(1-3):221-38.
  16. Jang WH, Lim KM, Kim K, Noh JY, Kang S, Chang YK, Chung JH. Low level of lead can in-duce phosphatidylserine exposure and erythrophagocytosis: a new mechanism underlying lead-associated anemia. Toxicol Sci. 2011;122(1):177-84. doi: 10.1093/toxsci/kfr079.
  17. Sakamoto M, Yasutake A, Domingo JL, Chan HM, Kubota M, Murata K. Relationships be-tween trace element concentrations in chorionic tissue of placenta and umbilical cord tissue: Potential use as indicators for prenatal exposure. Environ Int. 2013;60:106-11. doi: 10.1016/j.envint.2013.08.007.
  18. Gonzáles-Puebla E, González-Horta C, Infante-Ramírez R, Sanin LH, Levario-Carrillo M, Sánchez-Ramírez B. Altered expressions of MMP-2, MMP-9, and TIMP-2 in placentas from women ex-posed to lead. Hum Exp Toxicol. 2012;31(7):662-70. doi: 10.1177/0960327111431706.

Downloads

How to Cite

Shkolna, I., & Markevych, V. (2017). Features of content and balance of toxic trace elements in hair of mothers and their premature infants. Морфологія / Morphologia / Morfologìâ, 11(2), 52–57. https://doi.org/10.26641/1997-9665.2017.2.52-57

Issue

Vol. 11 No. 2 (2017)

Section

Статті

License

Copyright (c) 2018 Morphologia

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

 The authors reserve the right to authorship of their work and transfer to the Journal the right to the first publication of this work under the terms of a license Creative commons Attribution 4.0 International (CC BY 4.0), which allows other people to freely distribute the published work with a mandatory reference to the authors of the original work and the first publication of the work in this journal.
        By submitting a manuscript to the editorial office of the Journal ‘Morphologia’ authors agree to transfer the rights to protect and use the manuscript (all supplemental materials, particularly protected objects such as photos, drawings, diagrams, tables, etc.), including the reproduction in the press and distribution via the Internet; translation of the manuscript into any language; export and import of journal copies with the Authors’ article in order to make it available for public. Authors convey the rights mentioned above to the editorial office without any temporal or territorial limitation all over the world. 
        The Authors guarantee that they have the exclusive rights to use the material transferred to editorial office. Editors are not responsible to third parties for contraventions of warranty given by the Authors. The considered rights are transferred to the editorial office since the moment when the current issue is signed for publishing. Reproduction of materials published in the Journal by other individuals and legal entities is possible only with the consent of Editorial office, with the obligatory indication of the full bibliographic reference of the primary publication. The Authors reserve the right to use the published material, its fragments and parts for teaching materials, oral presentations, dissertation thesis prepararion with obligatory bibliographic citation of the original paper. Electron copy of the published article, downloaded from official journal web-site in .pdf format may be put by authors on the official web-site of their institutions, any other official resources with open access.