Morphogenetic transformations of the upper jaw rudiment and the structures of the maxillofacial region in human pre-fetuses aged 10-12 weeks of prenatal ontogenesis.

Authors

  • A. P. Oshurko Bukovinian State Medical University, Chernivtsi, Ukraine
  • I. Yu. Oliinyk Bukovinian State Medical University, Chernivtsi, Ukraine

DOI:

https://doi.org/10.26641/1997-9665.2017.3.13-20

Keywords:

prenatal ontogenesis, maxilla, maxillofacial region, human.

Abstract

Background. Based on the study of scientific literature, the authors concluded that the upper jaw in the perinatal period of ontogenesis is characterized by the diversity of the topical position of its processes and walls and predetermines the need for further anatomical studies of its prenatal ontogenesis. Having completed the first stage of the work, we considered it expedient to continue the study of the features of morphogenesis of the maxillofacial region in the dynamics of the pre-fetal period of human ontogenesis in the 10th -12th weeks of fetal developmentas a prospect of further researches. Objective. To study the features of the morphogenesis of the upper jaw and some structures of the human maxillofacial region in the dynamics of the 10th - 12th weeks of the prenatal ontogenesis. Material and methods. The study was conducted on 21 specimens of human pre-fetuses with 42.2-79.0 mm of crown-rump length (10-12 weeks of intrauterine development) using the methods of macroscopy, morphometry, manufacturing and microscopy of a series of sequential histological sections of human embryonic specimens and that of histochemistry. Results. During the 10th week of the intrauterine development (IUG), one can clearly identify the newly formed branches of the mandible, formed by the hyaline cartilaginous tissue, in the structure of the human maxillofacial region. In the histogenetically modeled bony basis of the mandible it is possible to recognize the alveolar grooves well-filled with mesenchyma cells as well as blood vessels and nerves. The bone plates, forming the alveolar grooves, open towards the side of the tooth buds. During the 11-12th weeks of the human IUG a complete separation of the oral and nasal cavities is finished, there is a further formation of the oral cavity vestibule, morphological transformations in the hard and soft tissues of the organs and structures of the maxillofacial region continue to increase due to the establishment of reciprocal relationships between the various tissue rudiments, therefore, it can be argued that there is a formed bony basis of the upper and lower jaws; their surrounding connective tissue structures and chewing muscles differentiate rapidly. Conclusion. Based on the study of the histogenesis features of the maxillofacial region in the embryonic [15] and pre-fetal periods of prenatal ontogenesis, one can conclude that on the completion of the 12th week of human IUG there are all prerequisites for an in-depth study to find out the features of the structure (density) and mineral composition of bone tissue of the human upper jaw in the dynamics of the fetal period of the prenatal ontogenesis.

References

  1. Akhtemiychuk YuT, Slobodyan OM, Khmara TV, Oliinyk IYu, Zavolovych AY, Pronyayev DV, authors; Akhtemiychuk YuT, editor. Narysy perynatal'noyi anatomiyi [Essays on perina-tal anatomy]. Chernivtsi: BDMU; 2011. 300 p. Ukrainian.
  2. Tsyhykalo OV, Popova IS, Kuzniak NB, Palis SYu, Shostenko AA, Dronyk II. [Current sci-entific investigations on maldevelopment of face (review of literature)]. Bukovinian Medical Herald. 2017;1:230–4. Ukrainian.
  3. Pechalova PF, Poriazova EG, Pavlov NV. Residual cyst of the jaws. Curierul medical. 2011;5:15–7.
  4. Ferros IN, Mora MJ, Obeso IF, Jimenez P, Martinez-Insua A. The nasomaxillary complex and the cranial base in artificial cranial deformation: relationships from a geometric morphometric study. Eur J Orthod. 2015 Aug;37(4):403-11. doi: 10.1093/ejo/cju066.
  5. Tsyhykalo O, Kuzniak N, Popova I, Oliinyk I, Dmytrenko R, Perebyinis P, Horytskyi Y. Peculi-arities of the upper lip morphogenesis and its rela-tion to facial development. Galician medical journal. 2017;24(2), E2017217: 1–4. DOI: 10.21802/gmj.2017.2.17.
  6. Kryvets'kyi VV, Protsak TV, Haina NI, Kozar OM. [Morphogenesis of the maxillary sinus structure during human ontogenesis]. Young Scien-tist. 2015; (11, Pt 3):84–87. Ukrainian.
  7. Slobodian OM, Korchyns'ka NS. [X-ray anatomy and morphometry of the upper jaw in the second trimester of intrauterine development]. Ukrainskyi zhurnal klinichnoi ta laboratornoi medytsyny. 2013;8(3):98–101. Ukrainian.
  8. Slobodian OM, Korchyns'ka NS. [Modern findings of the structure of the upper jaw at an early stage of human ontogenesis]. Klіnіchna anatomіya ta operatyvna khіrurgіya. 2011;10(3):58–63. Ukrainian.
  9. Shapovalova EIu, Barsukov AN, Iunsi GA. [Age dynamics of the human maxillofacial apparatus development in the early period of prenatal ontogenesis]. Morfologiia. 2010;137(2):77-81. Russian.
  10. Borenstein M, Persico N, Kaihura C, Sonek J, Nicolaides KH. Frontomaxillary facial angle in chromosomally normal fetuses at 11 + 0 to 13 + 6 weeks. Ultrasound Obstet Gynecol. 2007 Oct;30(5):737-41.
  11. Faure JM, Captier G, Bäumler M, Boulot P. Sonographic assessment of normal fetal palate using three-dimensional imaging: a new technique. Ultrasound Obstet Gynecol. 2007 Feb;29(2):159-65.
  12. Snell RS. Clinical anatomy by Regions: 9-th Edition. LWW; Ninth, North American Edition, 2011. 768 p.
  13. Oliinyk IYu. [Ideas of integration in the study of early prenatal ontogenesis of the thyroid gland]. In: [Pathoanatomical diagnostics of human diseases: achievements, problems, perspectives. Materials of the All-Ukrainian Scientific and Practical Conference devoted to the 100th anniversary of the birth of Professor N.M. Shinkerman; 2007 May 21-22; Chernivtsi, Ukraine]. Chernivtsi: Meduniversytet; 2007. 130–135. Ukrainian.
  14. Oshurko AP, Oliinyk IYu. [Innovation in the study of the features of the structure of the hu-man upper jaw in the dynamics of prenatal ontogenesis]. In: [Materials of the 98th final scientific conference of the teaching staff of the Higher State Educational Institution of Ukraine "Bukovinian State Medical University"; 2017 February 13, 15, 20; Chernivtsi, Ukrainian]. Chernivtsi: Meduniversytet; 2017. 19–20. Ukrainian.
  15. Oshurko AP., Oliinyk IYu. [Morphogenesis of the upper jaw and separate structures of the maxillofacial area in the embryonic period of human prenatal ontogenesis]. Klinichna ta eksperymental'na patolohiya. 2017; 16(2):137–44. Ukrainian.
  16. Shmidt GA. [The periods of embryogenesis and postnatal ontogenesis in man and animals]. Arkh Anat Gistol Embriol. 1972 Aug;63(8):17-28. Russian

Downloads

How to Cite

Oshurko, A. P., & Oliinyk, I. Y. (2017). Morphogenetic transformations of the upper jaw rudiment and the structures of the maxillofacial region in human pre-fetuses aged 10-12 weeks of prenatal ontogenesis. Морфологія / Morphologia / Morfologìâ, 11(3), 13–20. https://doi.org/10.26641/1997-9665.2017.3.13-20

Issue

Vol. 11 No. 3 (2017)

Section

Статті

License

Copyright (c) 2018 Morphologia

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

 The authors reserve the right to authorship of their work and transfer to the Journal the right to the first publication of this work under the terms of a license Creative commons Attribution 4.0 International (CC BY 4.0), which allows other people to freely distribute the published work with a mandatory reference to the authors of the original work and the first publication of the work in this journal.
        By submitting a manuscript to the editorial office of the Journal ‘Morphologia’ authors agree to transfer the rights to protect and use the manuscript (all supplemental materials, particularly protected objects such as photos, drawings, diagrams, tables, etc.), including the reproduction in the press and distribution via the Internet; translation of the manuscript into any language; export and import of journal copies with the Authors’ article in order to make it available for public. Authors convey the rights mentioned above to the editorial office without any temporal or territorial limitation all over the world. 
        The Authors guarantee that they have the exclusive rights to use the material transferred to editorial office. Editors are not responsible to third parties for contraventions of warranty given by the Authors. The considered rights are transferred to the editorial office since the moment when the current issue is signed for publishing. Reproduction of materials published in the Journal by other individuals and legal entities is possible only with the consent of Editorial office, with the obligatory indication of the full bibliographic reference of the primary publication. The Authors reserve the right to use the published material, its fragments and parts for teaching materials, oral presentations, dissertation thesis prepararion with obligatory bibliographic citation of the original paper. Electron copy of the published article, downloaded from official journal web-site in .pdf format may be put by authors on the official web-site of their institutions, any other official resources with open access.